Water

Water

SCHEMBL4098929

O.O.[RbH]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL11388551 1.00
Water SCHEMBL21980711 1.00
Water SCHEMBL5507851 1.00
Water SCHEMBL23364121 0.82
Water SCHEMBL18545 0.82
Water SCHEMBL9655782 0.82
Water SCHEMBL23209776 0.82
Water SCHEMBL5455356 0.82
Water SCHEMBL20993977 0.82
Water SCHEMBL21056037 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103524514-A Preparation method for (3aS,6aR)-1,3-dibenzyltetrahydro-1H-furo[3,4-d]imidazole-2,4-dione NORTHEAST PHARMACEUTICAL GROUP CO LTD 2014-01-22 CN claimed
EP-0641814-B1 Process for the regeneration of a catalyst from polyalkylene polyols MITSUI CHEMICALS INC (JP) 2000-03-15 EP claimed
US-5545712-A Preparation process for polyoxyalkylene polyol MITSU TOATSU CHEMICALS, INC. (JP) 1996-08-13 US claimed
US-5468840-A Preparation process of polyoxyalkylene polyols and process of alkylene oxide recovery MITSUI TOATSU CHEMICALS, INC. (JP) 1995-11-21 US claimed
EP-0641814-A1 Process for the regeneration of a catalyst from polyalkylene polyols MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-03-08 EP claimed
CN-117756609-B Preparation method of 3-methyl phenetole 万华化学集团股份有限公司 2025-02-18 CN disclosed
US-12046756-B2 Cellulose derivative composition for secondary battery binder and method of preparing composition for secondary battery electrode comprising the same ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2024-07-23 US disclosed
CN-118292105-A Multifunctional inorganic compound crystal and preparation method and application thereof 中国科学院福建物质结构研究所 2024-07-05 CN disclosed
CN-118048686-A Birefringent crystal material, method of making, and optical device 北京师范大学 2024-05-17 CN disclosed
CN-117756609-A Preparation method of 3-methyl phenetole 万华化学集团股份有限公司 2024-03-26 CN disclosed
CN-117187955-A Inorganic multifunctional crystal and preparation method and application thereof 中国科学院福建物质结构研究所 2023-12-08 CN disclosed
CN-116532090-A Natural gas purification material, preparation method and purification process thereof 昆山市恒安工业气体有限公司 2023-08-04 CN disclosed
EP-0108486-B1 PREPARATION OF ZEOLITES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-02-17 EP disclosed
US-4705674-A Synthesis of zeolite EU-13 from a reaction mixture containing tetramethylammonium compound IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-11-10 US disclosed
EP-0105679-B1 ZEOLITES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-06-16 EP disclosed
US-4581211-A METHANOL-TO-HYDROCARBONS CONVERSION CATALYSTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-04-08 US disclosed
EP-0077624-B1 ZEOLITE SYNTHESIS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-03-12 EP disclosed
EP-0108486-A1 Preparation of zeolites IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-05-16 EP disclosed
EP-0105679-A2 Zeolites IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-04-18 EP disclosed
EP-0077624-A2 Zeolite synthesis IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-04-27 EP disclosed