SCHEMBL4099548

SCHEMBL4099548

CCCCCCCCCC(=O)Oc1cc(C=Cc2ccc(O)cc2)cc(OC(=O)CCCCCCCCC)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 3/20 0.50
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 2/20 0.50
MAPT P10636 2/20 0.50
CYP1A1 P04798 2/20 0.50
ALOX5 P09917 2/20 0.50
PTGS2 P35354 2/20 0.50
CYP1B1 Q16678 2/20 0.50
NPC1 O15118 1/20 0.50
ABL1 P00519 1/20 0.50
ABCB1 P08183 1/20 0.50
GAA P10253 1/20 0.50
BCR P11274 1/20 0.50
NQO2 P16083 1/20 0.50
PTGS1 P23219 1/20 0.50
MAPK1 P28482 1/20 0.50
RAB9A P51151 1/20 0.50
GFER P55789 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2517639 1.00 TTR (0.50) TTRKMT2AKDM4EMEN1MAPT
SCHEMBL2515023 1.00 TTR (0.50) TTRKMT2AKDM4EMEN1MAPT
SCHEMBL2521977 1.00 TTR (0.50) TTRKMT2AKDM4EMEN1MAPT
SCHEMBL4107289 1.00 TTR (0.50) TTRKMT2AKDM4EMEN1MAPT
SCHEMBL4091795 1.00 TTR (0.50) TTRKMT2AKDM4EMEN1MAPT
SCHEMBL4101923 1.00 TTR (0.50) TTRKMT2AKDM4EMEN1MAPT
SCHEMBL2514977 0.96 PTGS2 (0.51) TTRKMT2AKDM4EMEN1MAPT
SCHEMBL1044464 0.96 PTGS2 (0.51) TTRKMT2AKDM4EMEN1MAPT
SCHEMBL1044590 0.96 PTGS2 (0.51) TTRKMT2AKDM4EMEN1MAPT
SCHEMBL4096915 0.96 PTGS2 (0.51) TTRKMT2AKDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9295621-B2 Emulsion cosmetic compositions containing resveratrol derivatives and silicone surfactant ELC MANAGEMENT LLC (US) 2016-03-29 US disclosed
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant ELC MANAGEMENT LLC 2009-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant SMURF1, CUTA, SMURF2 TTR 1952/4885KMT2A 1425/4885KDM4E 1074/4885
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent SMARCC1, RARG, RARA TTR 2561/4885KMT2A 1387/4885KDM4E 2286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.