SCHEMBL2514977

SCHEMBL2514977

CCCCCCCC(=O)Oc1cc(O)cc(C=Cc2ccc(O)cc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.51
CYP1A1 P04798 4/20 0.51
TTR P02766 3/20 0.51
ALOX5 P09917 3/20 0.51
CYP1B1 Q16678 3/20 0.51
ALB P02768 1/20 0.48
CISD1 Q9NZ45 2/20 0.48
TOP2A P11388 2/20 0.47
MIF P14174 1/20 0.47
KDM4E B2RXH2 3/20 0.46
MEN1 O00255 3/20 0.46
MAPT P10636 3/20 0.46
KMT2A Q03164 3/20 0.46
NPC1 O15118 2/20 0.46
ABL1 P00519 2/20 0.46
ABCB1 P08183 2/20 0.46
GAA P10253 2/20 0.46
BCR P11274 2/20 0.46
NQO2 P16083 2/20 0.46
PTGS1 P23219 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4098539 1.00 PTGS2 (0.51) PTGS2CYP1A1TTRALOX5CYP1B1
SCHEMBL4091528 1.00 PTGS2 (0.51) PTGS2CYP1A1TTRALOX5CYP1B1
SCHEMBL1042432 1.00 PTGS2 (0.51) PTGS2CYP1A1TTRALOX5CYP1B1
SCHEMBL2516564 1.00 PTGS2 (0.51) PTGS2CYP1A1TTRALOX5CYP1B1
SCHEMBL4096915 1.00 PTGS2 (0.51) PTGS2CYP1A1TTRALOX5CYP1B1
SCHEMBL2514429 1.00 PTGS2 (0.51) PTGS2CYP1A1TTRALOX5CYP1B1
SCHEMBL4103357 1.00 PTGS2 (0.51) PTGS2CYP1A1TTRALOX5CYP1B1
SCHEMBL1044464 1.00 PTGS2 (0.51) PTGS2CYP1A1TTRALOX5CYP1B1
SCHEMBL1044590 1.00 PTGS2 (0.51) PTGS2CYP1A1TTRALOX5CYP1B1
SCHEMBL2515023 0.96 TTR (0.50) PTGS2CYP1A1TTRALOX5CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9861564-B2 Valeric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT, LLC (US) 2018-01-09 US disclosed
US-9782335-B2 Malic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2017-10-10 US disclosed
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-10-20 US disclosed
EP-2445511-B1 SKIN REPAIR COMPOSITIONS COMPRISING CIRCADIAN GENE ACTIVATORS AND A SYNERGISTIC COMBINATION OF SIRT1 GENE ACTIVATORS ELC MAN LLC (US) 2016-09-07 EP disclosed
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-08-11 US disclosed
US-9358194-B2 Succinic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2016-06-07 US disclosed
US-9295621-B2 Emulsion cosmetic compositions containing resveratrol derivatives and silicone surfactant ELC MANAGEMENT LLC (US) 2016-03-29 US disclosed
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-02-11 US disclosed
US-9180316-B2 Butyric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-11-10 US disclosed
US-9162083-B2 Linoleic and Linolenic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-10-20 US disclosed
US-8084496-B2 Resveratrol ferulate compounds and compositions ELC MANAGEMENT LLC (US) 2011-12-27 US disclosed
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2011-10-13 US disclosed
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions MAES DANIEL H 2010-08-26 US disclosed
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2010-04-01 US disclosed
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN ELC MANAGEMENT LLC 2009-02-19 US disclosed
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives RB1, SIRT1, EP300 PTGS2 3838/4885CYP1A1 1440/4885TTR 723/4885
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone SQLE, SMURF1, PIK3R1 PTGS2 3228/4885CYP1A1 2625/4885TTR 3013/4885
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions FER, FOLR1, FOLR2 PTGS2 2446/4885CYP1A1 419/4885TTR 1081/4885
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN CUTA, ERCC1, OGG1 PTGS2 3235/4885CYP1A1 253/4885TTR 1842/4885
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 PTGS2 3235/4885CYP1A1 253/4885TTR 1842/4885
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions CUTA, SUV39H1, RARA PTGS2 2796/4885CYP1A1 348/4885TTR 518/4885
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant SMURF1, CUTA, SMURF2 PTGS2 3901/4885CYP1A1 2419/4885TTR 1952/4885
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent CUTA, LRAT, RARA PTGS2 2396/4885CYP1A1 1737/4885TTR 1922/4885
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent SMARCC1, RARG, RARA PTGS2 3031/4885CYP1A1 1950/4885TTR 2561/4885
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 PTGS2 3235/4885CYP1A1 253/4885TTR 1842/4885
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ME1, ME2, ME3 PTGS2 2574/4885CYP1A1 786/4885TTR 2746/4885
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions SUCNR1, SIRT1, SUCLA2 PTGS2 1728/4885CYP1A1 1271/4885TTR 3410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.