Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786080 | 0.90 | HTT (0.30) | HTT | |
| SCHEMBL5874105 | 0.87 | ALDH1A1 (0.33) | — | |
| SCHEMBL1642934 | 0.84 | CA2 (0.35) | — | |
| SCHEMBL5894043 | 0.84 | LMNA (0.41) | — | |
| SCHEMBL8032018 | 0.80 | TSHR (0.40) | — | |
| SCHEMBL28457599 | 0.76 | ELANE (0.30) | — | |
| SCHEMBL15153153 | 0.70 | ALDH1A1 (0.32) | HTT | |
| SCHEMBL13254028 | 0.69 | CYP1A2 (0.38) | HTT | |
| SCHEMBL1257515 | 0.66 | ALDH1A1 (0.42) | — | |
| SCHEMBL2962372 | 0.66 | DPP4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090226392-A1 | Phosphate-Binding Polymers for Oral Administration | GELTEX, INC. | 2009-09-10 | — | — | US | disclosed |
| US-7459151-B2 | Phosphate-binding polymers for oral administration | GENZYME CORPORATION (US) | 2008-12-02 | — | — | US | disclosed |
| US-20060171916-A1 | Phosphate-binding polymers for oral administration | HOLMES-FARLEY STEPHEN R | 2006-08-03 | — | — | US | disclosed |
| US-7014846-B2 | Phosphate-binding polymers for oral administration | GENZYME CORPORATION (US) | 2006-03-21 | — | — | US | disclosed |
| US-6858203-B2 | Method of making phosphate-binding polymers for oral administration | GENZYME CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| US-20040191212-A1 | Phosphate-binding polymers for oral administration | GENZYME CORPORATION (US) | 2004-09-30 | — | — | US | disclosed |
| US-20030133902-A1 | Method of making phosphate-binding polymers for oral administration | GELTEX PHARMACEUTICALS, INC. | 2003-07-17 | — | — | US | disclosed |
| US-6509013-B1 | Water insoluble crosslinked allyl amine homo- or copolymer and carrier; removing phosphate from gastrointestinal tract; hyperphosphatemia | GELTEX PHARMACEUTICALS, INC. | 2003-01-21 | — | — | US | disclosed |
| WO-1998042355-A1 | PHOSPHATE-BINDING POLYMERS COMBINED WITH A CALCIUM SUPPLEMENT FOR ORAL ADMINISTRATION | GELTEX PHARMACEUTICALS, INC. (US) | 1998-10-01 | — | — | WO | disclosed |
| US-5667775-A | TREATMENT OF HYPERPHOSPHATEMIA, ION EXCHANGING, CATIONIC POLYMERS, REMOVAL OF PHOSPHATE FROM GASTROINTESTINAL TRACT | GELTEX PHARMACEUTICALS, INC. (US) | 1997-09-16 | — | — | US | disclosed |
| WO-1996021454-A1 | PHOSPHATE-BINDING POLYMERS FOR ORAL ADMINISTRATION | GELTEX PHARMACEUTICALS, INC. (US) | 1996-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226392-A1 | Phosphate-Binding Polymers for Oral Administration | PHPT1, SLC34A2, ALPI | HTT 2786/4885 |
| US-20030133902-A1 | Method of making phosphate-binding polymers for oral administration | SI, PHPT1, ALPI | HTT 2223/4885 |
| US-20040191212-A1 | Phosphate-binding polymers for oral administration | PHPT1, SLC34A2, ALPI | HTT 2786/4885 |
| US-20060171916-A1 | Phosphate-binding polymers for oral administration | PHPT1, SLC34A2, ALPI | HTT 2786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.