SCHEMBL4101284

SCHEMBL4101284

O=[N+]([O-])c1cccc(S(=O)(=O)Nc2ccccc2)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.78
ALDH1A1 P00352 5/20 0.76
CA2 P00918 2/20 0.71
CA12 O43570 1/20 0.71
CA9 Q16790 1/20 0.71
AR P10275 1/20 0.69
DDX3X O00571 1/20 0.66
CA1 P00915 1/20 0.65
MMP1 P03956 1/20 0.65
MMP2 P08253 1/20 0.65
MMP9 P14780 1/20 0.65
MMP8 P22894 1/20 0.65
MMP13 P45452 1/20 0.65
KMT2A Q03164 5/20 0.64
MEN1 O00255 3/20 0.63
LMNA P02545 2/20 0.61
MAPT P10636 1/20 0.61
MAPK1 P28482 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
GAA P10253 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL893934 0.91 CA2 (0.71) PGRALDH1A1CA2CA12CA9
SCHEMBL5228114 0.87 ALDH1A1 (0.71) PGRALDH1A1CA2ARDDX3X
SCHEMBL5037028 0.87 ALDH1A1 (0.71) PGRALDH1A1CA2CA12CA9
SCHEMBL5233742 0.87 ALDH1A1 (0.71) PGRALDH1A1CA2ARDDX3X
SCHEMBL15043012 0.87 ALDH1A1 (0.71) PGRALDH1A1CA2CA12CA9
SCHEMBL23928394 0.87 ALDH1A1 (0.71) PGRALDH1A1CA2ARDDX3X
SCHEMBL13970848 0.87 ALDH1A1 (0.71) PGRALDH1A1CA2ARDDX3X
SCHEMBL95740 0.87 ALDH1A1 (0.71) PGRALDH1A1CA2CA12CA9
SCHEMBL15043011 0.85 ALDH1A1 (0.66) PGRALDH1A1CA2DDX3XCA1
SCHEMBL8248683 0.85 ALDH1A1 (0.65) PGRALDH1A1CA2DDX3XCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4551478-A 3-Nitrobenzene sulfonanilide derivatives and fungicidal compositions for the control of plant diseases containing same MITSUI TOATSU CHEMICALS, INC. (JP) 1985-11-05 US claimed
US-12427798-B2 Heat-sensitive recording composition NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-09-30 US disclosed
EP-3636446-B1 RECORDING MATERIAL, RECORDING SHEET AND USE OF A COMPOUND AS COLOUR-DEVELOPING AGENT NIPPON SODA CO (JP) 2025-04-16 EP disclosed
US-20250001788-A1 HEAT-SENSITIVE RECORDING COMPOSITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-01-02 US disclosed
EP-4442467-A1 THERMAL RECORDING COMPOSITION Nippon Kayaku Kabushiki Kaisha (JP) 2024-10-09 EP disclosed
EP-4442468-A1 HEAT-SENSITIVE RECORDING COMPOSITION Nippon Kayaku Kabushiki Kaisha (JP) 2024-10-09 EP disclosed
US-20240326501-A1 HEAT-SENSITIVE RECORDING COMPOSITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2024-10-03 US disclosed
WO-2023100900-A1 THERMAL RECORDING COMPOSITION 日本化薬株式会社 2023-06-08 WO disclosed
WO-2023100902-A1 HEAT-SENSITIVE RECORDING COMPOSITION 日本化薬株式会社 2023-06-08 WO disclosed
US-11529819-B2 Recording material and compound NIPPON SODA CO., LTD. (JP) 2022-12-20 US disclosed
WO-2001028537-A2 BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS ARROW THERAPEUTICS LIMITED (GB) 2001-04-26 WO disclosed
EP-0841919-A4 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO INC (US) 1999-02-24 EP disclosed
EP-0841919-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE Merck & Co., Inc. (US) 1998-05-20 EP disclosed
US-5710171-A ANTICANCER AND ANTITUMOR AGENTS MERCK & CO., INC. (US) 1998-01-20 US disclosed
WO-1996037204-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1996-11-28 WO disclosed
US-4551478-A 3-Nitrobenzene sulfonanilide derivatives and fungicidal compositions for the control of plant diseases containing same MITSUI TOATSU CHEMICALS, INC. (JP) 1985-11-05 US disclosed
US-4551478-A 3-Nitrobenzene sulfonanilide derivatives and fungicidal compositions for the control of plant diseases containing same MITSUI TOATSU CHEMICALS, INC. (JP) 1985-11-05 US disclosed
US-4551478-A 3-Nitrobenzene sulfonanilide derivatives and fungicidal compositions for the control of plant diseases containing same MITSUI TOATSU CHEMICALS, INC. (JP) 1985-11-05 US disclosed
US-4497828-A 3-Nitro-4-methylbenzene sulfon-2-chloro-4-nitroanilide and fungicidal composition for the control of plant diseases containing same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1985-02-05 US disclosed
US-4289847-A 2-EQUIVALENT YELLOW COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11529819-B2 Recording material and compound H1-0, DOT1L, H1-4 PGR 2184/4885ALDH1A1 1091/4885CA2 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.