Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | PGR | P06401 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | DDX3X | O00571 | 1/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.57 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.57 |
| ▸ | EDNRB | P24530 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101284 | 0.87 | PGR (0.78) | ALDH1A1PGRKMT2AARPKM | |
| SCHEMBL15043012 | 0.86 | ALDH1A1 (0.71) | ALDH1A1PGRKMT2AARCA1 | |
| SCHEMBL95740 | 0.86 | ALDH1A1 (0.71) | ALDH1A1PGRKMT2AARCA1 | |
| SCHEMBL5233742 | 0.86 | ALDH1A1 (0.71) | ALDH1A1PGRKMT2AARCA1 | |
| SCHEMBL5228114 | 0.86 | ALDH1A1 (0.71) | ALDH1A1PGRKMT2AARCA1 | |
| SCHEMBL13970848 | 0.86 | ALDH1A1 (0.71) | ALDH1A1PGRKMT2AARCA1 | |
| SCHEMBL12167777 | 0.84 | PGR (0.92) | ALDH1A1PGRKMT2AARCA1 | |
| SCHEMBL14125535 | 0.84 | CASP3 (0.76) | ALDH1A1KMT2APKMMEN1LMNA | |
| SCHEMBL29562764 | 0.84 | CASP3 (0.76) | ALDH1A1KMT2APKMMEN1LMNA | |
| SCHEMBL5037028 | 0.83 | ALDH1A1 (0.71) | ALDH1A1PGRKMT2AARCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355597-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT AND PREVENTION OF AVIAN PATHOGENIC E. COLI (APEC) | OHIO STATE INNOVATION FOUNDATION | 2023-11-09 | — | — | US | disclosed |
| US-20230174523-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174523-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | US | disclosed |
| US-11660294-B2 | Compounds, compositions, and methods for the treatment and prevention of avian pathogenic E. coli (APEC) | OHIO STATE INNOVATION FOUNDATION (US) | 2023-05-30 | — | — | US | disclosed |
| US-20210330655-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT AND PREVENTION OF AVIAN PATHOGENIC E. COLI (APEC) | OHIO STATE INNOVATION FOUNDATION | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174523-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | TRAP1, PINK1, TP53BP1 | ALDH1A1 2569/4885PGR 3572/4885KMT2A 4864/4885 |
| US-20230355597-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT AND PREVENTION OF AVIAN PATHOGENIC E. COLI (APEC) | FABP2, APC, AP1G1 | ALDH1A1 2256/4885PGR 4517/4885KMT2A 4473/4885 |
| US-11660294-B2 | Compounds, compositions, and methods for the treatment and prevention of avian pathogenic E. coli (APEC) | FABP2, APC, AP1G1 | ALDH1A1 2256/4885PGR 4517/4885KMT2A 4473/4885 |
| US-20210330655-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT AND PREVENTION OF AVIAN PATHOGENIC E. COLI (APEC) | FABP2, APC, AP1G1 | ALDH1A1 2256/4885PGR 4517/4885KMT2A 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.