Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | PGR | P06401 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | DDX3X | O00571 | 1/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.57 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101284 | 0.87 | PGR (0.78) | ALDH1A1PGRKMT2AARCA2 | |
| SCHEMBL13970848 | 0.86 | ALDH1A1 (0.71) | ALDH1A1PGRKMT2AARCA2 | |
| SCHEMBL5228114 | 0.86 | ALDH1A1 (0.71) | ALDH1A1PGRKMT2AARCA2 | |
| SCHEMBL95740 | 0.86 | ALDH1A1 (0.71) | ALDH1A1PGRKMT2AARCA2 | |
| SCHEMBL5233742 | 0.86 | ALDH1A1 (0.71) | ALDH1A1PGRKMT2AARCA2 | |
| SCHEMBL23928394 | 0.86 | ALDH1A1 (0.71) | ALDH1A1PGRKMT2AARCA2 | |
| SCHEMBL12167777 | 0.84 | PGR (0.92) | ALDH1A1PGRKMT2AARCA2 | |
| SCHEMBL9208267 | 0.83 | CA2 (0.71) | ALDH1A1KMT2ACA2CA1MMP1 | |
| SCHEMBL5037028 | 0.83 | ALDH1A1 (0.71) | ALDH1A1PGRKMT2AARCA2 | |
| SCHEMBL5228757 | 0.82 | ALDH1A1 (0.70) | ALDH1A1PGRKMT2AARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166553-A1 | ANTIMETASTATIC COMPOUNDS | UNIV BRIGHAM YOUNG (US) | 2016-06-16 | — | — | US | disclosed |
| US-20130158035-A1 | ANTIMETASTATIC COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158035-A1 | ANTIMETASTATIC COMPOUNDS | MET, HGFAC, HGF | ALDH1A1 855/4885PGR 848/4885KMT2A 3928/4885 |
| US-20160166553-A1 | ANTIMETASTATIC COMPOUNDS | MET, HGFAC, HGF | ALDH1A1 855/4885PGR 848/4885KMT2A 3928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.