Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.54 |
| ▸ | PNLIP | P16233 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30105484 | 1.00 | PTPN1 (0.54) | PTPN1PTPN2PNLIPCYP19A1RPS6KA5 | |
| SCHEMBL4104413 | 0.82 | PTPN1 (0.54) | PTPN1PTPN2PNLIPCYP19A1RPS6KA5 | |
| SCHEMBL26250198 | 0.79 | ALDH1A1 (0.46) | PTPN1PTPN2PNLIPCYP19A1RPS6KA5 | |
| SCHEMBL25436073 | 0.78 | PTPN2 (0.64) | PTPN1PTPN2PNLIPCYP19A1RPS6KA5 | |
| SCHEMBL25435120 | 0.78 | PTPN2 (0.64) | PTPN1PTPN2PNLIPCYP19A1RPS6KA5 | |
| SCHEMBL25433754 | 0.78 | PTPN2 (0.64) | PTPN1PTPN2PNLIPCYP19A1RPS6KA5 | |
| SCHEMBL25434992 | 0.78 | PTPN2 (0.64) | PTPN1PTPN2PNLIPCYP19A1RPS6KA5 | |
| SCHEMBL25394431 | 0.77 | PTPN2 (0.67) | PTPN1PTPN2PNLIPCYP19A1RPS6KA5 | |
| SCHEMBL25395835 | 0.77 | PNLIP (0.58) | PTPN1PTPN2PNLIPCYP19A1RPS6KA5 | |
| SCHEMBL25395895 | 0.77 | PTPN2 (0.67) | PTPN1PTPN2PNLIPCYP19A1RPS6KA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076136-A1 | THERAPEUTIC AGENT | ENOKI TATSUJI | 2009-03-19 | — | — | US | disclosed |
| US-20070060641-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-03-15 | — | — | US | disclosed |
| EP-1627632-A1 | THERAPEUTIC AGENT | TAKARA BIO INC. (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076136-A1 | THERAPEUTIC AGENT | GPR119, IAPP, FABP4 | PTPN1 2182/4885PTPN2 1854/4885PNLIP 14/4885 |
| US-20070060641-A1 | Therapeutic agent | GPR119, IAPP, FABP4 | PTPN1 2182/4885PTPN2 1854/4885PNLIP 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.