Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26173840 | 0.88 | KDM4E (0.46) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4104976 | 0.86 | ADORA2B (0.59) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL2464364 | 0.83 | KMT2A (0.52) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL27344419 | 0.76 | EZH2 (0.46) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL30735950 | 0.76 | EZH2 (0.46) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7071371 | 0.76 | KDM4E (0.42) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9921194 | 0.76 | KDM4E (0.48) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31457433 | 0.74 | SMN1; SMN2 (0.54) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL2330055 | 0.74 | SMN1; SMN2 (0.54) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1635171 | 0.73 | KDM4E (0.54) | KDM4EALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183187-A1 | QUINAZOLINE COMPOUNDS AS INHIBITORS OF PREMATURE TERMINATION CODONS | CENTRE NAT RECH SCIENT (FR) | 2023-06-15 | — | — | US | disclosed |
| WO-2021228945-A1 | QUINAZOLINE COMPOUNDS AS INHIBITORS OF PREMATURE TERMINATION CODONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-11-18 | — | — | WO | disclosed |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | KDM4E 308/4885ALDH1A1 1963/4885KMT2A 322/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | KDM4E 251/4885ALDH1A1 1279/4885KMT2A 555/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | KDM4E 419/4885ALDH1A1 1073/4885KMT2A 949/4885 |
| US-20230183187-A1 | QUINAZOLINE COMPOUNDS AS INHIBITORS OF PREMATURE TERMINATION CODONS | UPF1, NUDT21, REV1 | KDM4E 2993/4885ALDH1A1 4190/4885KMT2A 2885/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | KDM4E 1258/4885ALDH1A1 1610/4885KMT2A 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.