Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KMO | O15229 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31266408 | 1.00 | HPGD (0.55) | HPGDMEN1KMT2AKMOTSHR | |
| SCHEMBL3668982 | 0.86 | HPGD (0.53) | HPGDKMOTSHRHDAC3HDAC4 | |
| SCHEMBL31299787 | 0.85 | KDM4E (0.51) | HPGDMEN1KMT2AKMOTSHR | |
| SCHEMBL1348885 | 0.85 | KDM4E (0.51) | HPGDMEN1KMT2AKMOTSHR | |
| SCHEMBL23294373 | 0.85 | MEN1 (0.50) | HPGDMEN1KMT2ATSHRRAB9A | |
| SCHEMBL9015106 | 0.85 | TSHR (0.61) | HPGDMEN1KMT2AKMOTSHR | |
| SCHEMBL6810549 | 0.83 | L3MBTL1 (0.57) | HPGDKMOTSHRHDAC3HDAC4 | |
| SCHEMBL6990537 | 0.83 | HPGD (0.53) | HPGDMEN1KMT2ATSHRRAB9A | |
| SCHEMBL25268811 | 0.83 | HPGD (0.53) | HPGDKMOTSHRHDAC3HDAC4 | |
| SCHEMBL30481570 | 0.83 | HPGD (0.53) | HPGDKMOTSHRHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698511-B | 1, 3-diaryl-5-alkoxy pyrazole compound and preparation method and application thereof | 福州大学 | 2020-05-08 | — | — | CN | claimed |
| CN-107162978-B | A kind of tri- substituted pyrazole compounds of 1,3,5- and its preparation method and application | 福州大学 | 2019-06-07 | — | — | CN | claimed |
| CN-107162978-A | A kind of 1,3,5 3 substituted pyrazole compounds and its preparation method and application | 福州大学 | 2017-09-15 | — | — | CN | claimed |
| CN-116568135-B | Herbicidal derivatives | Syngenta Crop Protection JSC (CH) | 2026-05-26 | — | — | CN | disclosed |
| EP-4581016-A1 | HERBICIDAL PYRIDONE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2025-07-09 | — | — | EP | disclosed |
| EP-4532482-A1 | HERBICIDAL DERIVATIVES | Syngenta Crop Protection AG (CH) | 2025-04-09 | — | — | EP | disclosed |
| CN-119731155-A | Herbicidal pyridone derivatives | 先正达农作物保护股份公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119421873-A | Herbicidal derivatives | 先正达农作物保护股份公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119301109-A | Herbicidal derivatives | 先正达农作物保护股份公司 | 2025-01-10 | — | — | CN | disclosed |
| EP-4479382-A1 | HERBICIDAL QUINOLONE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2024-12-25 | — | — | EP | disclosed |
| CN-118679148-A | Herbicidal quinolone derivatives | 先正达农作物保护股份公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-107162978-A | A kind of 1,3,5 3 substituted pyrazole compounds and its preparation method and application | 福州大学 | 2017-09-15 | — | — | CN | disclosed |
| WO-2012149157-A2 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | BIOENERGENIX (US) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012149157-A2 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | BIOENERGENIX (US) | 2012-11-01 | — | — | WO | disclosed |
| US-20120277224-A1 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | BIOENERGENIX (US) | 2012-11-01 | — | — | US | disclosed |
| US-20120277224-A1 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | BIOENERGENIX (US) | 2012-11-01 | — | — | US | disclosed |
| US-20120277224-A1 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | BIOENERGENIX (US) | 2012-11-01 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| EP-1851232-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | Prosidion Limited (GB) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006085118-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | PROSIDION LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277224-A1 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | PASK, PDXK, PANK2 | HPGD 824/4885MEN1 3040/4885KMT2A 3661/4885 |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | TPH1, HTR3B, HTR1A | HPGD 935/4885MEN1 2481/4885KMT2A 2634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.