Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL411553 | 0.88 | CSNK2A2 (0.33) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL411858 | 0.65 | LMNA (0.46) | — | |
| SCHEMBL29697484 | 0.62 | CSNK2A2 (0.36) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL17965689 | 0.62 | CSNK2A2 (0.36) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29697534 | 0.62 | KMT2A (0.45) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL410618 | 0.61 | MAPT (0.50) | — | |
| SCHEMBL20343323 | 0.57 | ALDH1A1 (0.32) | — | |
| SCHEMBL13865236 | 0.57 | CASP3 (0.36) | — | |
| SCHEMBL316573 | 0.56 | LMNA (0.51) | — | |
| SCHEMBL4152740 | 0.55 | LMNA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716314-B2 | Isotopologues of thalidomide | CELGENE CORPORATION (US) | 2014-05-06 | — | — | US | disclosed |
| US-20120064004-A1 | ISOTOPOLOGUES OF THALIDOMIDE | CELGENE CORPORATION | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064004-A1 | ISOTOPOLOGUES OF THALIDOMIDE | CDK4, FKBP8, FKBP1A | CSNK2A2 1098/4885CSNK2B 1534/4885CSNK2A1 1349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.