Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 7/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 6/20 | 0.41 |
| ▸ | F3 | P13726 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.40 |
| ▸ | PRMT7 | Q9NVM4 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4115790 | 0.83 | F9 (0.59) | F9IMPDH2LRRK2C1SROCK1 | |
| SCHEMBL7902184 | 0.79 | F7 (0.57) | F9LRRK2ROCK1NPC1RAB9A | |
| SCHEMBL12545728 | 0.76 | F9 (0.55) | F9LRRK2NPC1LMNARAB9A | |
| SCHEMBL17244531 | 0.74 | F9 (0.52) | F9LRRK2C1SROCK1F7 | |
| SCHEMBL8149138 | 0.72 | ROCK1 (0.58) | C1SROCK1LMNAPRSS1PRSS2 | |
| SCHEMBL4100589 | 0.71 | MAPT (0.52) | RAB9ASMN1; SMN2KDRPLAU | |
| SCHEMBL23988833 | 0.68 | ALDH1A1 (0.51) | C1SROCK1PRSS1PRSS2PRSS3 | |
| SCHEMBL1232547 | 0.67 | F9 (0.67) | F9C1SROCK1F7F3 | |
| SCHEMBL335640 | 0.66 | F7 (0.56) | F9LRRK2ROCK1F7F3 | |
| SCHEMBL16457017 | 0.66 | ROCK2 (0.65) | F9ROCK1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263621-B2 | Tartrate derivatives for use as coagulation factor IXa inhibitors | SANOFI (FR) | 2012-09-11 | — | — | US | disclosed |
| US-20090233961-A1 | TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | SANOFI-AVENTIS (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233961-A1 | TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | TFPI, TFPI2, F9 | F9 3/4885IMPDH2 1467/4885LRRK2 4359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.