Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12113774 | 0.94 | — | — | |
| SCHEMBL409950 | 0.90 | PRKCA (0.32) | PRKCATSHRPRKCEPRKCQPRKCD | |
| SCHEMBL332526 | 0.90 | PRKCA (0.32) | PRKCATSHRPRKCEPRKCQPRKCD | |
| SCHEMBL15353761 | 0.89 | TSHR (0.35) | PRKCATSHRPRKCEPRKCQPRKCD | |
| SCHEMBL14942321 | 0.86 | — | — | |
| SCHEMBL12113832 | 0.83 | — | — | |
| SCHEMBL10038850 | 0.82 | TSHR (0.31) | TSHR | |
| SCHEMBL410384 | 0.82 | TSHR (0.36) | PRKCATSHRPRKCEPRKCQPRKCD | |
| SCHEMBL14706868 | 0.82 | — | — | |
| SCHEMBL14330404 | 0.81 | TSHR (0.45) | PRKCATSHRPRKCEPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049922-B1 | ACRYLOYL MATERIALS FOR MOLDED PLASTICS | JOHNSON & JOHNSON VISION CARE (US) | 2016-07-13 | — | — | EP | disclosed |
| US-8637589-B2 | Silicone prepolymer solutions | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-8637589-B2 | Silicone prepolymer solutions | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-8569538-B2 | Acryloyl materials for molded plastics | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569538-B2 | Acryloyl materials for molded plastics | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-8399539-B2 | Soluble silicone prepolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120065348-A1 | SOLUBLE SILICONE PREPOLYMERS | TORAY INDUSTRIES, INC. (JP) | 2012-03-15 | — | — | US | disclosed |
| US-8080622-B2 | Soluble silicone prepolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-12-20 | — | — | US | disclosed |
| US-8080622-B2 | Soluble silicone prepolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-12-20 | — | — | US | disclosed |
| US-8053539-B2 | Prepared by purifying acrylic siloxanyl containing monomers by distillation in the presence of at least one polymerization inhibitor which can be an alkylhydroquinone or a hydroxynaphthalene; without substantial amounts of polymerization product(s) and without discoloration; contact lenses | JOHNSON & JOHNSON VISION CARE INC. (US) | 2011-11-08 | — | — | US | disclosed |
| US-20110077322-A1 | Silicone Prepolymer Solutions | TORAY INDUSTRIES, INC. (JP) | 2011-03-31 | — | — | US | disclosed |
| US-7897654-B2 | Silicone prepolymer solutions | JOHNSON & JOHNSON VISION CARE INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-20090171026-A1 | SILICONE PREPOLYMER SOLUTIONS | JOHNSON & JOHNSON VISION CARE, INC. | 2009-07-02 | — | — | US | disclosed |
| US-20090005528-A1 | SOLUBLE SILICONE PREPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. | 2009-01-01 | — | — | US | disclosed |
| US-20080004401-A1 | SILOXANYL MATERIALS FOR MOLDED PLASTICS | JOHNSON & JOHNSON VISION CARE, INC. | 2008-01-03 | — | — | US | disclosed |
| US-20080004383-A1 | ACRYLOYL MATERIALS FOR MOLDED PLASTICS | TORAY INDUSTRIES, INC. (JP) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005528-A1 | SOLUBLE SILICONE PREPOLYMERS | NOS3, NOS2, PCNA | PRKCA 3443/4885TSHR 4182/4885PRKCE 3754/4885 |
| US-20080004383-A1 | ACRYLOYL MATERIALS FOR MOLDED PLASTICS | ACR, HAAO, PORCN | PRKCA 3665/4885TSHR 4861/4885PRKCE 3744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.