Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.60 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.60 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.60 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.60 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.54 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 6/20 | 0.44 |
| ▸ | CDC25A | P30304 | 5/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15874389 | 0.84 | DUSP3 (0.57) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| SCHEMBL15874387 | 0.84 | DUSP3 (0.57) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| SCHEMBL4111722 | 0.82 | PLA2G2A (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| SCHEMBL29367218 | 0.81 | TRPM2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| SCHEMBL4105636 | 0.76 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Epipolygodial SCHEMBL21322435 | 0.75 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Epipolygodial SCHEMBL13855685 | 0.75 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Polygodial SCHEMBL21633831 | 0.75 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Polygodial SCHEMBL258239 | 0.75 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 | |
| Epipolygodial SCHEMBL29370854 | 0.75 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076136-A1 | THERAPEUTIC AGENT | ENOKI TATSUJI | 2009-03-19 | — | — | US | claimed |
| US-20070060641-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-03-15 | — | — | US | claimed |
| EP-1627632-A1 | THERAPEUTIC AGENT | TAKARA BIO INC. (JP) | 2006-02-22 | — | — | EP | claimed |
| US-20090076136-A1 | THERAPEUTIC AGENT | ENOKI TATSUJI | 2009-03-19 | — | — | US | disclosed |
| US-20070060641-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-03-15 | — | — | US | disclosed |
| EP-1627632-A1 | THERAPEUTIC AGENT | TAKARA BIO INC. (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076136-A1 | THERAPEUTIC AGENT | GPR119, IAPP, FABP4 | CHRNB2 4095/4885CHRNB4 3876/4885CHRNA3 4249/4885 |
| US-20070060641-A1 | Therapeutic agent | GPR119, IAPP, FABP4 | CHRNB2 4095/4885CHRNB4 3876/4885CHRNA3 4249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.