Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11981276 | 1.00 | CHRNA7 (0.35) | CHRNA7CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL11960043 | 1.00 | CHRNA7 (0.35) | CHRNA7CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL11981277 | 0.82 | AOC3 (0.38) | TSHRMEN1KMT2AATMTDP1 | |
| SCHEMBL4121057 | 0.82 | AOC3 (0.38) | TSHRMEN1KMT2AATMTDP1 | |
| SCHEMBL4121060 | 0.82 | AOC3 (0.38) | TSHRMEN1KMT2AATMTDP1 | |
| SCHEMBL11981324 | 0.81 | RIPK1 (0.47) | CYP3A4CYP2C9CYP2C19TSHRMEN1 | |
| SCHEMBL4115448 | 0.81 | RIPK1 (0.47) | CYP3A4CYP2C9CYP2C19TSHRMEN1 | |
| SCHEMBL4115450 | 0.81 | RIPK1 (0.47) | CYP3A4CYP2C9CYP2C19TSHRMEN1 | |
| SCHEMBL11981271 | 0.79 | CES2 (0.43) | — | |
| SCHEMBL4124879 | 0.79 | CES2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236976-B2 | Processes for highly enantio- and diastereoselective synthesis of acyclic epoxy alcohols and allylic epoxy alcohols | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-08-07 | — | — | US | disclosed |
| US-20090163728-A1 | Processes for Highly Enantio- and Diastereoselective Synthesis of Acyclic Epoxy Alcohols and Allylic Epoxy Alcohols | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163728-A1 | Processes for Highly Enantio- and Diastereoselective Synthesis of Acyclic Epoxy Alcohols and Allylic Epoxy Alcohols | ADH1C, ADH1A, ADH5 | CHRNA7 3020/4885CYP3A4 106/4885CYP2C9 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.