SCHEMBL411680

SCHEMBL411680

CNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.62
EPHX2 P34913 1/20 0.58
CASP3 P42574 2/20 0.51
FABP5 Q01469 3/20 0.50
FABP7 O15540 2/20 0.50
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
MDM4 O15151 1/20 0.46
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31173373 1.00 KMT2A (0.62) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL29728458 1.00 KMT2A (0.62) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL21297386 0.89 EPHX2 (0.55) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL402111 0.87 KMT2A (0.68) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL21332462 0.86 KMT2A (0.66) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL16253851 0.86 KMT2A (0.51) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL20126921 0.86 KMT2A (0.60) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL13993335 0.85 KMT2A (0.58) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL1800381 0.85 KMT2A (0.64) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL30238049 0.85 KMT2A (0.64) KMT2AEPHX2CASP3FABP5FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238458-A1 COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF PURDUE RESEARCH FOUNDATION 2024-07-18 US disclosed
US-20240218342-A1 SITE-SPECIFIC GLYCAN REMODELING OF LYSOSOMAL ENZYMES AND APPLICATIONS THEREOF UNIVERSITY OF MARYLAND, COLLEGE PARK 2024-07-04 US disclosed
EP-4389822-A1 CROSSLINKABLE ACRYLIC RUBBER COMPOSITION Unimatec Co., Ltd. (JP) 2024-06-26 EP disclosed
CN-117279655-A Pharmaceutical use of cyclic peptide compounds 中外制药株式会社 2023-12-22 CN disclosed
US-20230398224-A1 TARGETED PLASMA PROTEIN DEGRADATION NOVARTIS AG (CH) 2023-12-14 US disclosed
WO-2023234426-A1 ANTIBODY-MULTIDRUG CONJUGATE UBE株式会社 2023-12-07 WO disclosed
US-11827920-B2 Nanostructure, a biosensor including the nanostructure, and a screening method POSTECH Research and Business Development Foundation (KR) 2023-11-28 US disclosed
WO-2023225661-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-11-23 WO disclosed
EP-3508476-B1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION SHANGHAI KECHOW PHARMA INC (CN) 2023-11-22 EP disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 US disclosed
US-20070078094-A1 Guanidinium delivery carriers NITTO DENKO CORPORATION (JP) 2007-04-05 US disclosed
US-20070078094-A1 Guanidinium delivery carriers NITTO DENKO CORPORATION (JP) 2007-04-05 US disclosed
US-20070072802-A1 Peptide nucleic acid based guanidinium compounds NITTO DENKO CORPORATION (JP) 2007-03-29 US disclosed
US-20070010561-A1 PRENYLATION INHIBITORS AND METHODS OF THEIR SYNTHESIS AND USE PHARMACEUTICAL PRODUCT DEVELOPMENT, LLC 2007-01-11 US disclosed
US-7160735-B2 Tagged microparticle compositions and methods MONOGRAM BIOSCIENCES, INC. (US) 2007-01-09 US disclosed
EP-1724269-A1 Heteroaryl-carboxylic acid (sulfamoyl alkyl) amide - derivatives as factor Xa inhibitors Sanofi-Aventis Deutschland GmbH (DE) 2006-11-22 EP disclosed
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-01-26 US disclosed
US-20040210041-A1 Multimeric proteins for use in the treatment and detection of cell proliferative disorders ARBOGAST CHRISTOPHE (FR) 2004-10-21 US disclosed
US-20040072849-A1 Dioxanes and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-04-15 US disclosed
CN-1343206-A Cyclocompound FUJISAWA PHARMACEUTICAL CO (JP) 2002-04-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR KMT2A 3040/4885EPHX2 2665/4885CASP3 1537/4885
US-20240218342-A1 SITE-SPECIFIC GLYCAN REMODELING OF LYSOSOMAL ENZYMES AND APPLICATIONS THEREOF GAA, MAN2B1, M6PR KMT2A 3330/4885EPHX2 3591/4885CASP3 4794/4885
US-20070078094-A1 Guanidinium delivery carriers SLC2A9, SLC29A2, SLC2A4 KMT2A 4242/4885EPHX2 2166/4885CASP3 3296/4885
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy ITGA4, ITGB4, ITGA1 KMT2A 3460/4885EPHX2 4011/4885CASP3 2064/4885
US-20240238458-A1 COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF FAP, FIBP, FGFR1 KMT2A 4193/4885EPHX2 2557/4885CASP3 1444/4885
US-20070010561-A1 PRENYLATION INHIBITORS AND METHODS OF THEIR SYNTHESIS AND USE FNTA, RCE1, GGPS1 KMT2A 4201/4885EPHX2 1146/4885CASP3 4516/4885
US-20040072849-A1 Dioxanes and uses thereof UTS2R, HDAC5, AMDHD2 KMT2A 178/4885EPHX2 1101/4885CASP3 4036/4885
US-20070072802-A1 Peptide nucleic acid based guanidinium compounds SLC29A1, SLC29A2, SLC28A1 KMT2A 4167/4885EPHX2 4625/4885CASP3 3437/4885
US-20230398224-A1 TARGETED PLASMA PROTEIN DEGRADATION M6PR, ASGR1, IGF2R KMT2A 2277/4885EPHX2 2827/4885CASP3 3970/4885
US-20040210041-A1 Multimeric proteins for use in the treatment and detection of cell proliferative disorders MKI67, TP53, VHL KMT2A 3846/4885EPHX2 4192/4885CASP3 2875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.