Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4120655 | 0.88 | NFE2L2 (0.39) | KAT6AAKR1C3MEP1BGAAMTNR1B | |
| SCHEMBL4119867 | 0.85 | MAPT (0.41) | KAT6AGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4131739 | 0.82 | MEP1B (0.42) | AKR1C3MEP1BMTNR1BALDH1A1HSD11B1 | |
| SCHEMBL3655896 | 0.82 | KAT6A (0.42) | KAT6AMEP1BMTNR1BPGRHSD11B1 | |
| Fumaric Acid SCHEMBL3645618 | 0.82 | KAT6A (0.45) | KAT6AMEP1BGAAMEN1KMT2A | |
| Fumaric Acid SCHEMBL4132158 | 0.82 | KAT6A (0.45) | KAT6AMEP1BGAAMEN1KMT2A | |
| SCHEMBL2839246 | 0.79 | EDNRA (0.41) | GAASMN1; SMN2MEN1KMT2AMTNR1B | |
| SCHEMBL4132674 | 0.78 | AKR1C3 (0.37) | KAT6AAKR1C3KMT2AMTNR1BTDP1 | |
| SCHEMBL2837977 | 0.77 | GAA (0.39) | GAASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL4130269 | 0.76 | KAT6A (0.33) | KAT6AAKR1C3KMT2ATDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | KAT6A 4058/4885AKR1C3 1218/4885MEP1B 940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.