Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 2/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126579 | 0.87 | SLC16A3 (0.41) | SLC16A3SLC16A1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4135868 | 0.84 | NAMPT (0.39) | SLC16A3SLC16A1SMN1; SMN2ALDH1A1FPR1 | |
| SCHEMBL4118804 | 0.84 | LMNA (0.36) | P2RX7SLC16A3SLC16A1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4126274 | 0.83 | GAA (0.40) | SLC16A3SLC16A1SMN1; SMN2ALDH1A1FPR1 | |
| SCHEMBL3700362 | 0.83 | SLC16A3 (0.38) | GCKSLC16A3SLC16A1FPR1CNR1 | |
| Hydrochloric Acid SCHEMBL3704802 | 0.82 | MAPK14 (0.35) | GCKSLC16A3SLC16A1FPR1CNR1 | |
| SCHEMBL4135079 | 0.82 | SLC16A3 (0.37) | P2RX7SLC16A3SLC16A1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4125774 | 0.82 | SMN1; SMN2 (0.36) | P2RX7SLC16A3SLC16A1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4135506 | 0.81 | SLC16A3 (0.37) | SLC16A3SLC16A1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4126447 | 0.81 | NAMPT (0.41) | P2RX7SLC16A3SLC16A1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | P2RX7 1303/4885GCK 420/4885SLC16A3 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.