Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 4/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.35 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135506 | 0.89 | SLC16A3 (0.37) | SLC16A3SLC16A1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4125774 | 0.89 | SMN1; SMN2 (0.36) | SLC16A3SLC16A1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4135868 | 0.87 | NAMPT (0.39) | SLC16A3SLC16A1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4126579 | 0.85 | SLC16A3 (0.41) | SLC16A3SLC16A1SMN1; SMN2ALDH1A1RIPK1 | |
| SCHEMBL4125459 | 0.84 | ATM (0.36) | SMN1; SMN2ALDH1A1CNR1MAPTATM | |
| SCHEMBL4126103 | 0.84 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1CNR1MAPTNPC1 | |
| SCHEMBL4126274 | 0.84 | GAA (0.40) | SLC16A3SLC16A1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3705041 | 0.83 | SLC16A3 (0.39) | SLC16A3SLC16A1RIPK1LMNAPKM | |
| SCHEMBL4118804 | 0.83 | LMNA (0.36) | SLC16A3SLC16A1SMN1; SMN2ALDH1A1LMNA | |
| Fumaric Acid SCHEMBL3691572 | 0.83 | SLC16A3 (0.36) | SLC16A3SLC16A1SMN1; SMN2ALDH1A1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | SLC16A3 2809/4885SLC16A1 2925/4885SMN1; SMN2 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.