Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | F7 | P08709 | 2/20 | 0.41 |
| ▸ | F3 | P13726 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1631787 | 0.89 | GBA1 (0.51) | ALDH1A1MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL1631443 | 0.89 | NPC1 (0.45) | ALDH1A1MEN1MAPTKMT2AGBA1 | |
| SCHEMBL1631415 | 0.88 | GBA1 (0.45) | ALDH1A1MEN1MAPTKMT2AJAK3 | |
| SCHEMBL1630102 | 0.88 | CSNK2A2 (0.44) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL1632043 | 0.88 | ALDH1A1 (0.40) | ALDH1A1LMNAHPGDMEN1MAPT | |
| SCHEMBL1632558 | 0.87 | KCNA5 (0.42) | ALDH1A1LMNAHPGDMEN1MAPT | |
| SCHEMBL1629879 | 0.86 | GBA1 (0.39) | ALDH1A1MAPTGBA1ADRB2ADRB1 | |
| SCHEMBL1631828 | 0.86 | GBA1 (0.42) | ALDH1A1LMNAHPGDMAPTGBA1 | |
| SCHEMBL1632284 | 0.85 | CSNK2A2 (0.46) | LMNAMEN1MAPTHTTKMT2A | |
| SCHEMBL1630481 | 0.85 | CYP3A4 (0.41) | ALDH1A1MEN1MAPTKMT2AKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012126-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012126-A1 | Certain chemical entities, compositions, and methods | MYLK, MYH2, MYH10 | ALDH1A1 1756/4885LMNA 242/4885HPGD 1800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.