Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740705 | 0.69 | MCL1 (0.64) | CES2CES1MEN1KMT2AHPGD | |
| SCHEMBL21060836 | 0.67 | PTGS2 (0.41) | MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL134765 | 0.64 | MCL1 (0.62) | HTTGAACYP1A2POLBALDH1A1 | |
| SCHEMBL7029882 | 0.63 | CES2 (0.60) | CES2CES1GSK3BMEN1KMT2A | |
| SCHEMBL10919988 | 0.62 | CES2 (0.58) | CES2CES1GSK3BMEN1KMT2A | |
| SCHEMBL6826709 | 0.62 | CYP1A2 (0.33) | TSHRCYP1A2 | |
| SCHEMBL19650840 | 0.62 | HSD11B1 (0.60) | CES2CES1MEN1KMT2ALMNA | |
| SCHEMBL1855141 | 0.62 | HSD11B1 (0.60) | CES2CES1MEN1KMT2AHPGD | |
| SCHEMBL1835404 | 0.61 | MCL1 (0.36) | POLB | |
| SCHEMBL4023293 | 0.61 | HSD11B1 (0.63) | CES2CES1GSK3BLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595954-B1 | (4-TRIFLUORMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER IP GMBH (DE) | 2016-05-04 | — | — | EP | claimed |
| CN-103119020-B | (4-trifluoromethyl-3-thiobenzoyl) cyclohexanedione and the purposes as weedicide thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-12 | — | — | CN | claimed |
| US-8563779-B2 | (4-trifluoromethyl-3-thiobenzoyl)cyclohexanediones and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-10-22 | — | — | US | claimed |
| CN-103119020-A | (4-trifluormethyl-3-thiobenzoyl) cyclohexanediones and use thereof as herbicides | BAYER CROPSCIENCE AG | 2013-05-22 | — | — | CN | claimed |
| US-20120021902-A1 | (4-TRIFLUOROMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | claimed |
| CN-103119020-B | (4-trifluoromethyl-3-thiobenzoyl) cyclohexanedione and the purposes as weedicide thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-12 | — | — | CN | disclosed |
| CN-103119020-B | (4-trifluoromethyl-3-thiobenzoyl) cyclohexanedione and the purposes as weedicide thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-12 | — | — | CN | disclosed |
| CN-103119020-B | (4-trifluoromethyl-3-thiobenzoyl) cyclohexanedione and the purposes as weedicide thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-12 | — | — | CN | disclosed |
| US-8563779-B2 | (4-trifluoromethyl-3-thiobenzoyl)cyclohexanediones and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-10-22 | — | — | US | disclosed |
| US-8563779-B2 | (4-trifluoromethyl-3-thiobenzoyl)cyclohexanediones and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-10-22 | — | — | US | disclosed |
| JP-2013537523-A | — | — | 2013-10-03 | — | — | JP | disclosed |
| EP-2595954-A1 | (4-TRIFLUORMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | Bayer Intellectual Property GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| CN-103119020-A | (4-trifluormethyl-3-thiobenzoyl) cyclohexanediones and use thereof as herbicides | BAYER CROPSCIENCE AG | 2013-05-22 | — | — | CN | disclosed |
| WO-2012010574-A1 | (4-TRIFLUORMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | WO | disclosed |
| US-20120021902-A1 | (4-TRIFLUOROMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021902-A1 | (4-TRIFLUOROMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | CBR3, DDT, CYP4X1 | CES2 316/4885CES1 688/4885GSK3B 2725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.