Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580790 | 0.97 | LMNA (0.41) | LMNACHRM2PIK3CDCA12CA2 | |
| SCHEMBL29580455 | 0.97 | LMNA (0.41) | LMNACHRM2PIK3CDCA12CA2 | |
| SCHEMBL12039802 | 0.94 | LMNA (0.39) | LMNACHRM2PIK3CDCA12CA2 | |
| SCHEMBL8405817 | 0.94 | CHRM2 (0.48) | LMNACHRM2PIK3CDCA12CA2 | |
| SCHEMBL26406570 | 0.92 | CHRM2 (0.46) | LMNACHRM2PIK3CDALDH1A1KDM4C | |
| SCHEMBL5949010 | 0.91 | LMNA (0.48) | LMNACHRM2PIK3CDCA12CA2 | |
| SCHEMBL23934075 | 0.89 | ALDH1A1 (0.41) | LMNACHRM2PIK3CDCA12CA2 | |
| SCHEMBL10081590 | 0.89 | PIK3CD (0.48) | LMNACHRM2PIK3CDCA12CA2 | |
| SCHEMBL21117163 | 0.89 | LMNA (0.36) | LMNACHRM2PIK3CDCA12CA2 | |
| SCHEMBL9945708 | 0.89 | GGPS1 (0.38) | LMNACHRM2KDM4CKDM4APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067642-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2024-02-29 | — | — | US | disclosed |
| US-20230331722-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-10-19 | — | — | US | disclosed |
| US-11767330-B2 | Citrate salt, pharmaceutical compositions, and methods of making and using the same | FOGHORN THERAPEUTICS INC. (US) | 2023-09-26 | — | — | US | disclosed |
| US-11696959-B2 | Nanoparticle-cell construct with platinum anti-cancer agent | CITY OF HOPE (US) | 2023-07-11 | — | — | US | disclosed |
| US-20230142883-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-11 | — | — | US | disclosed |
| US-20190022246-A1 | SILICON NANOPARTICLE WITH PLATINUM ANTI-CANCER AGENT | CITY OF HOPE | 2019-01-24 | — | — | US | disclosed |
| US-20090093468-A1 | Peptide Deformylase Inhibitors | ARPIDA A/S (DK) | 2009-04-09 | — | — | US | disclosed |
| US-20070066672-A1 | Benzimidazole derivatives and use thereof as peptide deformylase inhibitors | ARPIDA A/S (DK) | 2007-03-22 | — | — | US | disclosed |
| EP-1732907-A1 | PEPTIDE DEFORMYLASE INHIBITORS | Arpida A/S (DK) | 2006-12-20 | — | — | EP | disclosed |
| US-7101940-B2 | Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2006-09-05 | — | — | US | disclosed |
| EP-1677785-A1 | BENZIMIDAZOLE DERIVATIVES AND USE THEREOF AS PEPTIDE DEFORMYLASE INHIBITORS | Arpida A/S (DK) | 2006-07-12 | — | — | EP | disclosed |
| US-7034173-B2 | Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2006-04-25 | — | — | US | disclosed |
| US-6953829-B2 | Catalyst system and the use thereof | BASELL POLYOLEFINE GMBH (DE) | 2005-10-11 | — | — | US | disclosed |
| WO-2005092872-A1 | PEPTIDE DEFORMYLASE INHIBITORS | ARPIDA A/S (DK) | 2005-10-06 | — | — | WO | disclosed |
| WO-2005037272-A1 | BENZIMIDAZOLE DERIVATIVES AND USE THEREOF AS PEPTIDE DEFORMYLASE INHIBITORS | ARPIDA A/S (DK) | 2005-04-28 | — | — | WO | disclosed |
| US-20030144434-A1 | Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins | EQUISTAR CHEMICALS, LP | 2003-07-31 | — | — | US | disclosed |
| US-20030013913-A1 | Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins | EQUISTAR CHEMICALS, LP | 2003-01-16 | — | — | US | disclosed |
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190022246-A1 | SILICON NANOPARTICLE WITH PLATINUM ANTI-CANCER AGENT | POLI, TP53, TOP2A | LMNA 2541/4885CHRM2 4879/4885PIK3CD 522/4885 |
| US-11696959-B2 | Nanoparticle-cell construct with platinum anti-cancer agent | CD47, TP53, CD63 | LMNA 2866/4885CHRM2 4869/4885PIK3CD 1242/4885 |
| US-20230331722-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | LMNA 172/4885CHRM2 4878/4885PIK3CD 1598/4885 |
| US-20070066672-A1 | Benzimidazole derivatives and use thereof as peptide deformylase inhibitors | PDF, MRPL21, PEPD | LMNA 1563/4885CHRM2 4409/4885PIK3CD 2215/4885 |
| US-20030144434-A1 | Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins | CBR1, COX6C, CBR3 | LMNA 1090/4885CHRM2 329/4885PIK3CD 3242/4885 |
| US-20230142883-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | LMNA 172/4885CHRM2 4878/4885PIK3CD 1598/4885 |
| US-11767330-B2 | Citrate salt, pharmaceutical compositions, and methods of making and using the same | CS, SMARCC2, SMARCC1 | LMNA 1765/4885CHRM2 4348/4885PIK3CD 37/4885 |
| US-20090093468-A1 | Peptide Deformylase Inhibitors | PDF, PEPD, MRPL21 | LMNA 2707/4885CHRM2 4607/4885PIK3CD 3654/4885 |
| US-20030013913-A1 | Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins | SCO2, CNOT1, CYC1 | LMNA 3058/4885CHRM2 1348/4885PIK3CD 1777/4885 |
| US-20240067642-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | LMNA 172/4885CHRM2 4878/4885PIK3CD 1598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.