Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MPL | P40238 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.44 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694580 | 0.86 | CTRB1 (0.48) | CYP2D6MPLALDH1A1MEN1THRB | |
| SCHEMBL6051301 | 0.85 | TTR (0.47) | CYP2D6MPLALDH1A1MEN1THRB | |
| SCHEMBL8979202 | 0.84 | CYP2D6 (0.49) | CYP2D6MPLALDH1A1MEN1THRB | |
| SCHEMBL10033897 | 0.83 | CYP2D6 (0.51) | CYP2D6MPLALDH1A1MEN1THRB | |
| SCHEMBL16817741 | 0.81 | CASP6 (0.54) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL3201539 | 0.81 | CASP6 (0.54) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL29475260 | 0.81 | CASP6 (0.54) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL16817740 | 0.80 | CASP6 (0.53) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL8100909 | 0.80 | CASP6 (0.53) | ALDH1A1MEN1THRBKMT2ATDP1 | |
| SCHEMBL3213538 | 0.80 | CYP2D6 (0.66) | CYP2D6MPLALDH1A1MEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501967-B2 | Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols | LONZA AG (CH) | 2013-08-06 | — | — | US | disclosed |
| US-20120316350-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 1-SUBSTITUTED-3-AMINOALCOHOLS | LONZA AG (CH) | 2012-12-13 | — | — | US | disclosed |
| US-8258338-B2 | Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols | LONZA AG (CH) | 2012-09-04 | — | — | US | disclosed |
| CN-101124196-B | Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols | LONZA AG | 2011-05-11 | — | — | CN | disclosed |
| US-20090156833-A1 | Process for the Preparation of Enantiomerically Pure 1-Substituted-3-Aminoalcohols | LONZA AG (CH) | 2009-06-18 | — | — | US | disclosed |
| CN-101124196-A | Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols | LONZA AG (CH) | 2008-02-13 | — | — | CN | disclosed |
| EP-1868983-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 1-SUBSTITUTED-3-AMINOALCOHOLS | LONZA AG (CH) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006087166-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 1-SUBSTITUTED-3-AMINOALCOHOLS | LONZA AG (CH) | 2006-08-24 | — | — | WO | disclosed |
| US-20060166869-A1 | Novel use of lipopeptide preparations | UNIVERSITE DE LIEGE INTERFACE ENTREPRISES-UNIVERSITE (BE) | 2006-07-27 | — | — | US | disclosed |
| EP-1528929-A1 | NOVEL USE OF LIPOPEPTIDE PREPARATIONS | Faculté Universitaire des Sciences Agronomiques de Gembloux (BE) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004002510-A1 | NOVEL USE OF LIPOPEPTIDE PREPARATIONS | FACULTE UNIVERSITAIRE DES SCIENCES AGRONOMIQUES DE GEMBLOUX (BE) | 2004-01-08 | — | — | WO | disclosed |
| US-20030203008-A1 | Preparation of collagen | GUNASEKARAN SUBRAMANIAN (US) | 2003-10-30 | — | — | US | disclosed |
| US-20030183575-A1 | METHOD OF MONITORING MEMBRANE SEPARATION PROCESSES | ECOLAB USA INC. | 2003-10-02 | — | — | US | disclosed |
| US-6548077-B1 | Using proteolytic enzyme and reducing agent; wound healing agent | GUNASEKARAN SUBRAMANIAN (US) | 2003-04-15 | — | — | US | disclosed |
| US-6127143-A | PRODUCING CONNECTIVE TISSUE PROTEINS; MIXING CONNECTIVE TISSUE PROTEIN AND PROTEOLYTIC ENZYME, INCUBATE WITH REDUCING AGENT, INCUBATE WITH SECOND PROTEOLYTIC ENZYME, INCUBATE WITH SOLUBLE AGENT, RECOVER CONNECTIVE TISSUE PROTEIN | GUNASEKARAN SUBRAMANIAN (US) | 2000-10-03 | — | — | US | disclosed |
| US-5814328-A | DELIPIDATION; COMPRESSION, DEHYDRATION, DISPERSION, DRYING; PHOSPHORYLATION | GUNASEKARAN SUBRAMANIAN (US) | 1998-09-29 | — | — | US | disclosed |
| US-4777246-A | 1-diazo-2-naphthol-4-sulfonic acid by iron-catalyzed diazotization | CIBA-GEIGY CORPORATION (US) | 1988-10-11 | — | — | US | disclosed |
| EP-0198800-B1 | PROCESS FOR THE PRODUCTION OF 1-DIAZO-2-NAPHTHOL-4-SULPHONIC ACID | CIBA-GEIGY AG (CH) | 1988-08-24 | — | — | EP | disclosed |
| EP-0198800-A1 | Process for the production of 1-diazo-2-naphthol-4-sulphonic acid | CIBA-GEIGY AG (CH) | 1986-10-22 | — | — | EP | disclosed |
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316350-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 1-SUBSTITUTED-3-AMINOALCOHOLS | CYP2S1, AKR1C3, AKR1B10 | CYP2D6 200/4885MPL 4793/4885ALDH1A1 99/4885 |
| US-20090156833-A1 | Process for the Preparation of Enantiomerically Pure 1-Substituted-3-Aminoalcohols | CYP2S1, AKR1C3, ADSL | CYP2D6 342/4885MPL 4631/4885ALDH1A1 122/4885 |
| US-20060166869-A1 | Novel use of lipopeptide preparations | LPXN, NGLY1, HASPIN | CYP2D6 4764/4885MPL 2128/4885ALDH1A1 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.