SCHEMBL5694580

SCHEMBL5694580

Nc1c(S(=O)(=O)O)cc2ccccc2c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 1/20 0.48
CYP2D6 P10635 1/20 0.47
MPL P40238 5/20 0.46
CTRC Q99895 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 1/20 0.46
APP P05067 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
ALOX12 P18054 1/20 0.46
SNCA P37840 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP1A2 P05177 2/20 0.45
TTR P02766 1/20 0.44
SUMO2 P61956 4/20 0.44
SUMO1 P63165 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11573727 0.88 CA1 (0.50) MPLCTRC
SCHEMBL4123954 0.86 CYP2D6 (0.47) CTRB1CYP2D6MPLCTRCALDH1A1
SCHEMBL6051301 0.85 TTR (0.47) CTRB1CYP2D6MPLCTRCALDH1A1
SCHEMBL10033897 0.83 CYP2D6 (0.51) CTRB1CYP2D6MPLCTRCALDH1A1
SCHEMBL27514313 0.83 ENPP2 (0.46) CYP2D6ALDH1A1MEN1APPMAPT
SCHEMBL10014029 0.83 CASP6 (0.55) CYP2D6ALDH1A1MEN1APPMAPT
SCHEMBL6454177 0.82 CYP2D6 (0.51) CTRB1CYP2D6MPLCTRCALDH1A1
SCHEMBL517711 0.81 CASP6 (0.54) ALDH1A1MEN1THRBHPGDKMT2A
SCHEMBL7790474 0.81 NT5E (0.57) CYP2D6ALDH1A1MEN1APPMAPT
Potassium SCHEMBL9695842 0.81 CYP2D6 (0.50) CTRB1CYP2D6MPLCTRCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1656551-A1 LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR Honeywell International Inc. (US) 2006-05-17 EP claimed
WO-2005019816-A1 LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR HONEYWELL INTERNATIONAL, INC. (US) 2005-03-03 WO claimed
US-6719810-B1 REACTING A PROTECTIVE ENTITY WITH A MOIETY HAVING THE CAPABILITY OF FORMING A COVALENT BOND WITH A NYLON FIBER TO CREATE A MODIFIED PROTECTIVE ENTITY THAT IS ADAPTED TO FORM A COVALENT BOND WITH A NYLON FIBER KELLY DAVID R (US) 2004-04-13 US claimed
US-6719810-B1 REACTING A PROTECTIVE ENTITY WITH A MOIETY HAVING THE CAPABILITY OF FORMING A COVALENT BOND WITH A NYLON FIBER TO CREATE A MODIFIED PROTECTIVE ENTITY THAT IS ADAPTED TO FORM A COVALENT BOND WITH A NYLON FIBER KELLY DAVID R (US) 2004-04-13 US disclosed
US-20010052154-A1 Covalently bonded protectors for nylon fibers, yarns and finished products KELLY DAVID R (US) 2001-12-20 US disclosed
US-5891230-A COLORING PAPER, TEXTILES ZENECA LIMITED (GB) 1999-04-06 US disclosed
EP-0872523-A2 Fiber-reactive azo dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-10-21 EP disclosed
US-5780602-A MONOAZO AND DISAZO FIBER REACTIVE DYES; DYEING AND FIXING PYSTAR TEXTILFARBEN GMBH & CO. KG (DE) 1998-07-14 US disclosed
US-4906737-A Azo dye of the pyridone series containing a fluoro-s-triazinyl fibre-reactive group CIBA-GEIGY CORPORATION (US) 1990-03-06 US disclosed
EP-0093369-B1 REACTIVE DYES BAYER AG (DE) 1986-07-23 EP disclosed
US-4507236-A Fibre-reactive dyes, containing both chloro and fluoro triazine radicals CIBA-GEIGY CORPORATION (US) 1985-03-26 US disclosed
EP-0093369-A2 Reactive dyes BAYER AG (DE) 1983-11-09 EP disclosed
US-4216166-A Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction AMERICAN CYANAMID COMPANY (US) 1980-08-05 US disclosed
US-4024123-A TEXTILES DUSSY PAUL 1977-05-17 US disclosed