Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234411 | 0.90 | DUT (0.32) | DUT | |
| SCHEMBL19460464 | 0.85 | DUT (0.39) | DUTALDH1A1 | |
| SCHEMBL4115638 | 0.83 | TSHR (0.39) | TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL1799910 | 0.79 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL19460463 | 0.76 | DUT (0.38) | DUT | |
| SCHEMBL17211882 | 0.76 | TSHR (0.51) | DUTTSHRALDH1A1 | |
| SCHEMBL284885 | 0.75 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL23067127 | 0.75 | LMNA (0.38) | DUTTSHR | |
| SCHEMBL7086769 | 0.75 | DUT (0.37) | DUTTSHR | |
| SCHEMBL19543597 | 0.75 | DUT (0.37) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253733-A1 | RAPAMYCIN CARBONATE ESTERS | BIOINTERACTIONS, LTD. (GB) | 2009-10-08 | — | — | US | claimed |
| US-20090253733-A1 | RAPAMYCIN CARBONATE ESTERS | BIOINTERACTIONS, LTD. (GB) | 2009-10-08 | — | — | US | disclosed |
| WO-2009122176-A2 | RAPAMYCIN CARBONATE ESTERS | BIOINTERACTIONS LTD (GB) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253733-A1 | RAPAMYCIN CARBONATE ESTERS | CEL, MTOR, RICTOR | DUT 4334/4885TSHR 2245/4885HPGD 3837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.