Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | DUT | P33316 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907714 | 0.89 | THRB (0.52) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1046104 | 0.84 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17211881 | 0.82 | TSHR (0.39) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29136601 | 0.82 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7086769 | 0.82 | DUT (0.37) | TSHRPOLBTDP1DUT | |
| SCHEMBL19460464 | 0.82 | DUT (0.39) | ALDH1A1DUT | |
| SCHEMBL13057763 | 0.81 | TSHR (0.38) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL182045 | 0.81 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL919922 | 0.80 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16696044 | 0.80 | ALDH1A1 (0.47) | TSHRALDH1A1DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150309210-A1 | HYDROPHILIZED CARBOSILOXANE VINYLIC MONOMERS | ALCON INC. (CH) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150309210-A1 | HYDROPHILIZED CARBOSILOXANE VINYLIC MONOMERS | VCL, MACF1, HCAR1 | TSHR 3251/4885THRB 3475/4885POLB 4519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.