SCHEMBL234411

SCHEMBL234411

C=COC(=O)OCCO[Si](C)(C)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4127902 0.90 DUT (0.33) DUT
SCHEMBL13028473 0.79 TSHR (0.52) DUT
SCHEMBL28519902 0.79 DUT (0.41) DUT
SCHEMBL28519906 0.79 DUT (0.41) DUT
SCHEMBL284797 0.78 TSHR (0.42)
SCHEMBL16587939 0.77 ALDH1A1 (0.48) DUT
SCHEMBL17243241 0.75 ATM (0.44) DUT
SCHEMBL8214522 0.74 BACE1 (0.31)
SCHEMBL17242155 0.74 DUT (0.37) DUT
SCHEMBL907714 0.74 THRB (0.52) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1080 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US claimed
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 US claimed
EP-4713721-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-03-25 EP claimed
EP-3759528-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
US-20250303615-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2025-10-02 US claimed
WO-2008076736-A2 ACTINICALLY CURABLE SILICONE HYDROGEL COPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2008-06-26 WO claimed
US-20080143003-A1 Actinically curable silicone hydrogel copolymers and uses thereof ALCON INC. (CH) 2008-06-19 US claimed
EP-0757033-B1 Vinyl carbonate and vinyl carbamate monomers for a contact lens material BAUSCH & LOMB (US) 1999-03-03 EP claimed
EP-0611367-B1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION BAUSCH & LOMB (US) 1997-06-25 EP claimed
EP-0396364-B1 Copolymers of vinyl carbonate and vinyl carbamate as contact lens material BAUSCH & LOMB (US) 1997-06-11 EP claimed
US-5610252-A Vinyl carbonate and vinyl carbamate contact lens material monomers BAUSCH & LOMB INCORPORATED (US) 1997-03-11 US claimed
EP-0757033-A2 Vinyl carbonate and vinyl carbamate monomers for a contact lens material BAUSCH & LOMB INCORPORATED (US) 1997-02-05 EP claimed
US-5449729-A Vinyl monomer and crosslinking agent and acrylates with styrene BAUSCH & LOMB INCORPORATED (US) 1995-09-12 US claimed
US-5070215-A Gas permeable contact lenses BAUSCH & LOMB INCORPORATED (US) 1991-12-03 US claimed
EP-0396364-A2 Novel vinyl carbonate and vinyl carbamate contact lens material monomers BAUSCH & LOMB INCORPORATED (US) 1990-11-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA DUT 3972/4885
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES CRYZ, STRA6, PHOSPHO1 DUT 4115/4885
US-12595368-B2 UV/HEVL-filtering contact lenses UACA, HSPA4L, RAD54L DUT 4484/4885
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES STRA6, CRYZ, SMCHD1 DUT 4268/4885
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES CRYZ, CRYAB, CRYAA DUT 4276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.