Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4130798 | 0.90 | LMNA (0.56) | TGFBR1LMNATDP1BRAFALDH1A1 | |
| SCHEMBL4796671 | 0.86 | LMNA (0.49) | TGFBR1LMNATDP1BRAFALDH1A1 | |
| SCHEMBL11573009 | 0.84 | ALDH1A1 (0.59) | TGFBR1LMNATDP1BRAFALDH1A1 | |
| SCHEMBL4596133 | 0.78 | MAPK1 (0.59) | ALDH1A1SMN1; SMN2MAPK1HTTKMT2A | |
| SCHEMBL2751718 | 0.76 | ALDH1A1 (0.37) | TGFBR1BRAFALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4131898 | 0.75 | ALDH1A1 (0.54) | LMNATDP1BRAFALDH1A1SMN1; SMN2 | |
| SCHEMBL4139611 | 0.75 | ALDH1A1 (0.58) | LMNATDP1BRAFALDH1A1SMN1; SMN2 | |
| SCHEMBL31666382 | 0.75 | SMN1; SMN2 (0.54) | LMNAALDH1A1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL10900697 | 0.75 | SMN1; SMN2 (0.54) | LMNAALDH1A1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL2753641 | 0.74 | MAPK1 (0.38) | ALDH1A1SMN1; SMN2KDM4EMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066643-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008062012-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |