Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 6/20 | 0.35 |
| ▸ | SI | P14410 | 6/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131197 | 0.85 | DYRK1A (0.33) | DYRK1AGSK3B | |
| SCHEMBL4119129 | 0.85 | DYRK1A (0.33) | GAASMN1; SMN2RAB9ADYRK1AGSK3B | |
| SCHEMBL3799055 | 0.85 | ALDH1A1 (0.36) | GAANPC1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL4132224 | 0.83 | DYRK1A (0.34) | DYRK1AGSK3B | |
| SCHEMBL4135881 | 0.82 | ICAM1 (0.35) | GAANPC1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL4119019 | 0.82 | LIPG (0.33) | DYRK1AGSK3B | |
| SCHEMBL4125114 | 0.82 | NPC1 (0.32) | NPC1RAB9ADYRK1AMEN1KMT2A | |
| SCHEMBL4130796 | 0.81 | MGAM (0.36) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL4130279 | 0.81 | MAPT (0.37) | NPC1SMN1; SMN2KDM4ERAB9AADAM17 | |
| SCHEMBL3652325 | 0.81 | NPC1 (0.34) | NPC1SMN1; SMN2KDM4ERAB9ADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | MGAM 1183/4885GAA 7/4885SI 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.