Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599895 | 0.83 | CYP2C9 (0.59) | PPARAMAPTCYP1A2MEN1CYP2C19 | |
| SCHEMBL5157805 | 0.82 | PPARA (0.50) | PPARAMAPTCYP1A2MEN1CYP2C19 | |
| SCHEMBL23849504 | 0.82 | PPARA (0.47) | PPARAMAPTCYP1A2MEN1CYP2C19 | |
| SCHEMBL9034965 | 0.81 | FBP1 (0.61) | PPARAMAPTCYP1A2MEN1CYP2C19 | |
| SCHEMBL13180019 | 0.80 | CYP2C9 (0.45) | PPARAMAPTCYP1A2MEN1CYP2C19 | |
| SCHEMBL16348228 | 0.80 | ACHE (0.55) | PPARAMAPTCYP1A2MEN1CYP2C19 | |
| SCHEMBL14934285 | 0.79 | PPARA (0.53) | PPARAMAPTCYP1A2MEN1CYP2C19 | |
| SCHEMBL10432851 | 0.79 | CYP2C9 (0.43) | PPARAMAPTCYP1A2MEN1CYP2C19 | |
| SCHEMBL581884 | 0.78 | PPARA (0.59) | PPARAMAPTCYP1A2MEN1CYP2C19 | |
| SCHEMBL1305941 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005672-A1 | ANTIDIABETIC AZAINDOLES AND DIAZAINDOLES | MERCK & CO., INC. (US) | 2009-01-08 | — | — | WO | disclosed |