SCHEMBL4134527

SCHEMBL4134527

CCOCCOc1ccnc(C(=O)O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.45
ALDH1A1 P00352 4/20 0.45
MAPT P10636 2/20 0.45
KDM6B O15054 1/20 0.45
TET3 O43151 1/20 0.45
KDM4A O75164 1/20 0.45
BBOX1 O75936 1/20 0.45
KDM5A P29375 1/20 0.45
KDM5C P41229 1/20 0.45
ASPH Q12797 1/20 0.45
KDM4D Q6B0I6 1/20 0.45
TET2 Q6N021 1/20 0.45
ALKBH5 Q6P6C2 1/20 0.45
KDM7A Q6ZMT4 1/20 0.45
KDM8 Q8N371 1/20 0.45
TET1 Q8NFU7 1/20 0.45
EGLN2 Q96KS0 1/20 0.45
FTO Q9C0B1 1/20 0.45
EGLN1 Q9GZT9 1/20 0.45
KDM4C Q9H3R0 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27639521 0.85 KDM4E (0.52) KDM4EALDH1A1MAPTKDM6BTET3
SCHEMBL2455403 0.84 TP53 (0.51) KDM4EALDH1A1MAPTKDM6BTET3
SCHEMBL10098352 0.84 KDM4E (0.47) KDM4EALDH1A1MAPTKDM6BTET3
SCHEMBL10986249 0.82 PLA2G2A (0.56) RARB
SCHEMBL28289083 0.81 RARB (0.42) KDM4EALDH1A1MAPTKMT2AMEN1
SCHEMBL29852409 0.78 KDM4E (0.53) KDM4EALDH1A1MAPTKDM6BTET3
SCHEMBL4069028 0.77 ALPL (0.46) MAPTRARBLMNA
SCHEMBL11378346 0.77 P4HTM (0.55) KDM4EALDH1A1MAPTKMT2AMEN1
SCHEMBL4078541 0.76 TP53 (0.43) KDM4EALDH1A1MAPTKDM6BTET3
SCHEMBL25030047 0.76 BCHE (0.48) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090200920-A1 Light-Emitting Material SOLVAY SA (BE) 2009-08-13 US disclosed
EP-1934302-A2 LIGHT-EMITTING MATERIAL Solvay SA (BE) 2008-06-25 EP disclosed
WO-2007042474-A2 LIGHT-EMITTING MATERIAL Solvay (Société Anonyme) (BE) 2007-04-19 WO disclosed
EP-1772507-A1 Light-emitting material SOLVAY (Société Anonyme) (BE) 2007-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090200920-A1 Light-Emitting Material CLTB, EML4, APOL1 KDM4E 755/4885ALDH1A1 1034/4885MAPT 292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.