Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GNRHR | P30968 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE6C | P51160 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131082 | 0.92 | MAPT (0.34) | MAPTALDH1A1KDM4ECNR2PDE5A | |
| SCHEMBL4139405 | 0.88 | KDM4E (0.34) | MAPTALDH1A1KDM4ENPSR1POLB | |
| SCHEMBL8034133 | 0.87 | KDM4E (0.36) | MAPTALDH1A1KDM4ECYP3A4PDE5A | |
| SCHEMBL4123024 | 0.86 | ALDH1A1 (0.36) | MAPTALDH1A1KDM4EPDE5APDE6C | |
| SCHEMBL8042659 | 0.86 | KDM4E (0.37) | MAPTALDH1A1KDM4ETSHRNPSR1 | |
| SCHEMBL8043252 | 0.86 | KDM4E (0.36) | MAPTALDH1A1KDM4EPDE5ANPSR1 | |
| SCHEMBL4117716 | 0.86 | SIGMAR1 (0.33) | MAPTALDH1A1KDM4ENPSR1SIGMAR1 | |
| SCHEMBL8042867 | 0.85 | KDM4E (0.33) | MAPTALDH1A1KDM4ENPSR1POLB | |
| SCHEMBL4132580 | 0.84 | KDM4E (0.35) | MAPTALDH1A1KDM4ENPSR1POLB | |
| SCHEMBL4127434 | 0.81 | KDM4E (0.35) | MAPTALDH1A1KDM4ECNR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071707-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2009-06-11 | — | — | WO | disclosed |