Water

Water

SCHEMBL4134758

O.c1c[nH]nn1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL4456796 1.00
Water SCHEMBL17460462 1.00
Water SCHEMBL28283070 1.00
Ammonia Solution, Strong SCHEMBL28220936 0.97
Hydrochloric Acid SCHEMBL6288509 0.97
Hydrochloric Acid SCHEMBL28859819 0.97
Water SCHEMBL5815301 0.97
Water SCHEMBL5310125 0.97
SCHEMBL30349526 0.96
SCHEMBL15545054 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106620825-B A kind of bi-component quick-acting haemostatic powder gel and its application 浙江大学 2019-11-12 CN claimed
CN-110251457-A A kind of antitumor sustained-release implant and preparation method thereof with strong adherency and hemostatic function 合肥工业大学 2019-09-20 CN claimed
CN-109252165-A A kind of preparation method for subtracting copper liquid subtracting copper composition and include the composition 苏州纳勒电子科技有限公司 2019-01-22 CN claimed
CN-107149700-A A kind of three component biological glues and its preparation and application 浙江大学 2017-09-12 CN claimed
CN-100475791-C Method for preparing 6-hydroxyl-3-cyanogen pyridine SHANDONG INST LIGHT INDUSTRY (CN) 2009-04-08 CN claimed
CN-101270082-A Method for preparing 6-hydroxyl-3-cyanogen pyridine SHANDONG INST LIGHT INDUSTRY (CN) 2008-09-24 CN claimed
CN-1064359-C Diindole heterocyclic compounds, preparing method and use thereof SHANGHAI INST ORGANIC CHEM (CN) 2001-04-11 CN claimed
CN-1224015-A Diindole heterocyclic compounds, preparing method and use thereof SHANGHAI INST ORGANIC CHEM (CN) 1999-07-28 CN claimed
US-20250206764-A1 TRIAZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID TRIAZOLE COMPOUND, COUPLING AGENT AND USES THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2025-06-26 US disclosed
CN-119823001-A Urea compounds antagonizing LPA1 receptor 大正制药株式会社 2025-04-15 CN disclosed
CN-114206832-B Urea compounds antagonizing LPA1 receptor 大正制药株式会社 2025-04-04 CN disclosed
EP-4501937-A1 TRIAZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID TRIAZOLE COMPOUND, COUPLING AGENT AND USES THEREOF Shikoku Chemicals Corporation (JP) 2025-02-05 EP disclosed
CN-118922427-A Triazole compound, synthesis method of triazole compound, coupling agent and application thereof 四国化成工业株式会社 2024-11-08 CN disclosed
CN-108383858-B Derivatives of imidazothiadiazoles and imidazopyrazines for the treatment of platelet aggregation 百时美施贵宝公司 2024-09-20 CN disclosed
CN-1042356-A 1, 4-diaza * derivatives and their pharmaceutical use EISAI CO LTD (JP) 1990-05-23 CN disclosed
CN-1040582-A New peptidase inhibitors MERRELL DOW PHARMA (US) 1990-03-21 CN disclosed
CN-1037704-A The glutaramide diuretic agents of enantiomorph PFIZER (US) 1989-12-06 CN disclosed
EP-0140731-A2 Natriuretic factors INSTITUT DE RECHERCHES CLINIQUES DE MONTREAL (CA) 1985-05-08 EP disclosed
EP-0000017-B1 1-(2-PHENYLETHYL)-TRIAZOLIUM SALTS, THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1981-09-30 EP disclosed
EP-0000017-A1 1-(2-Phenylethyl)-triazolium salts, their preparation and their use as fungicides BAYER AG (DE) 1978-12-20 EP disclosed