SCHEMBL4134974

SCHEMBL4134974

Cc1cc(-c2ccc(C(C)C)c(-c3cc(C)c(O)c(C)c3)c2C(C)C)cc(C)c1O.Cc1cc(C(C)(C)c2cc(C)c(O)c(C)c2)cc(C)c1O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CNR1 P21554 5/20 0.34
CNR2 P34972 5/20 0.34
ESR1 P03372 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
TRPA1 O75762 1/20 0.32
LMNA P02545 1/20 0.32
CHRM1 P11229 1/20 0.32
SLC6A2 P23975 1/20 0.32
ADRA1A P35348 1/20 0.32
HTR2B P41595 1/20 0.32
LDHA P00338 1/20 0.32
LDHB P07195 1/20 0.32
PTPN5 P54829 1/20 0.31
RORC P51449 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1885197 0.92 CA1 (0.41) CA1CA2CYP1A2TRPA1LMNA
SCHEMBL6676697 0.80 CA1 (0.41) CA1CA2CYP1A2TRPA1LMNA
SCHEMBL758758 0.77 CA1 (0.52) CA1CA2CYP1A2CYP2C9CYP2C19
SCHEMBL7056452 0.74 LMNA (0.39) ESR1CYP2C19TRPA1LMNACHRM1
SCHEMBL20244141 0.74 ALOX15 (0.43) CA1CA2ESR1CYP1A2CYP2C9
SCHEMBL11482666 0.74 ALOX15 (0.45) CA1CA2CNR1CNR2LMNA
SCHEMBL27509265 0.72 CA1 (0.47) CA1CA2CYP1A2CYP2C9CYP2C19
SCHEMBL13713036 0.72 CA2 (0.54) CA1CA2CNR1CNR2ESR1
SCHEMBL27353893 0.71 GABRA1 (0.54) CA1CA2CYP1A2CYP2C9CYP2C19
SCHEMBL11059669 0.70 CA1 (0.46) CA1CA2ESR1CYP1A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1440115-B1 CROSSLINKING OF UNSATURATED POLYESTERS BY THE USE OF HYDROXYLAMINE-ESTERS CIBA HOLDING INC (CH) 2009-08-05 EP disclosed
US-20090163621-A1 Process for improving color of polycondensates SIMON DIRK 2009-06-25 US disclosed
US-7358311-B2 Crosslinking of unsaturated polymers by the use of hydroxylamine-esters CIBA SPECIALTY CHEMICALS CORP. (US) 2008-04-15 US disclosed
US-7230042-B2 Flame retardant polymer compositions containing hydroxylamine esters CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-12 US disclosed
US-20070055047-A1 Molecular weight increase and modification of polycondensates CIBA SPECIALTY CHEMICALS CORP. 2007-03-08 US disclosed
US-20070027252-A1 Process for improving color of polycondensates CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-02-01 US disclosed
EP-1664181-B1 PROCESS FOR IMPROVING COLOR OF POLYCONDENSATES CIBA SC HOLDING AG (CH) 2006-12-20 EP disclosed
EP-1664153-A1 MOLECULAR WEIGHT INCREASE AND MODIFICATION OF POLYCONDENSATES Ciba SC Holding AG (CH) 2006-06-07 EP disclosed
US-20050203222-A1 Flame retardant polymer compositions containing hydroxylamine esters CIBA SPECIALTY CHEMICALS CORP. 2005-09-15 US disclosed
EP-1054031-B1 Increasing the molecular weight and modification of condensation polymers CIBA SC HOLDING AG (CH) 2005-08-24 EP disclosed
WO-2005030834-A1 MOLECULAR WEIGHT INCREASE AND MODIFICATION OF POLYCONDENSATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-04-07 WO disclosed
EP-1513893-A2 FLAME RETARDANT POLYMER COMPOSITIONS CONTAINING HYDROXYLAMINE ESTERS Ciba SC Holding AG (CH) 2005-03-16 EP disclosed
US-20040265509-A1 Crosslinking of unsaturated polymers by the use of hydroxylamine-esters CIBA SPECIALTY CHEMICALS CORP. 2004-12-30 US disclosed
EP-1440115-A1 CROSSLINKING OF UNSATURATED POLYMERS BY THE USE OF HYDROXYLAMINE-ESTERS Ciba SC Holding AG (CH) 2004-07-28 EP disclosed
WO-2003087211-A2 FLAME RETARDANT POLYMER COMPOSITIONS CONTAINING HYDROXYLAMINE ESTERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-10-23 WO disclosed
WO-2003029332-A1 CROSSLINKING OF UNSATURATED POLYMERS BY THE USE OF HYDROXYLAMINE-ESTERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-04-10 WO disclosed
US-6469078-B1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATE RECYCLATES FROM USEFUL MATERIAL COLLECTIONS CIBA SPECIALTY CHEMICALS CORPORATION 2002-10-22 US disclosed
EP-0931810-B1 Increasing the molecular weight and stabilisation of polycondensates with hindered amine diepoxides CIBA SC HOLDING AG (CH) 2002-02-27 EP disclosed
EP-1054031-A2 Increasing the molecular weight and modification of condensation polymers Ciba SC Holding AG (CH) 2000-11-22 EP disclosed
EP-0931810-A2 Increasing the molecular weight and stabilisation of polycondensates with hindered amine diepoxides Ciba SC Holding AG (CH) 1999-07-28 EP disclosed