SCHEMBL758758

SCHEMBL758758

Cc1cc(-c2c(C(C)C)ccc(C(C)C)c2-c2cc(C)c(O)c(C)c2)cc(C)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
LMNA P02545 4/20 0.45
SLC6A2 P23975 2/20 0.45
HTR2B P41595 2/20 0.45
TRPA1 O75762 2/20 0.45
CHRM1 P11229 1/20 0.45
ADRA1A P35348 1/20 0.45
GABRA1 P14867 5/20 0.43
GABRB1 P18505 4/20 0.43
PTGS1 P23219 4/20 0.42
PTGS2 P35354 2/20 0.42
GABRB2 P47870 3/20 0.41
CYP1A2 P05177 2/20 0.41
FAAH O00519 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
GABRG2 P18507 1/20 0.41
HTR2C P28335 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27353893 0.88 GABRA1 (0.54) CA1CA2LMNASLC6A2HTR2B
SCHEMBL1885197 0.84 CA1 (0.41) CA1CA2LMNASLC6A2HTR2B
SCHEMBL6676697 0.81 CA1 (0.41) CA1CA2LMNASLC6A2HTR2B
SCHEMBL6847775 0.80 GABRA1 (0.52) CA1CA2LMNASLC6A2HTR2B
SCHEMBL7054359 0.80 LMNA (0.47) CA1CA2LMNASLC6A2HTR2B
SCHEMBL29402386 0.79 ALDH1A1 (0.52) CA1CA2LMNASLC6A2HTR2B
SCHEMBL112575 0.79 ALDH1A1 (0.52) CA1CA2LMNASLC6A2HTR2B
SCHEMBL3661100 0.78 CA1 (0.56) CA1CA2LMNATRPA1GABRA1
SCHEMBL4134974 0.77 CA1 (0.34) CA1CA2LMNASLC6A2HTR2B
SCHEMBL3688286 0.76 ALDH1A1 (0.48) LMNASLC6A2HTR2BTRPA1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4355808-A1 OLIGOESTERS COMPRISING RESORCINOL AND ISO- AND/OR TEREPHTHALIC ACID, CORRESPONDING POLYESTER CARBONATES AND THEIR PREPARATION Covestro Deutschland AG (DE) 2024-04-24 EP claimed
WO-2022263319-A1 OLIGOESTERS COMPRISING RESORCINOL AND ISO- AND/OR TEREPHTHALIC ACID, CORRESPONDING POLYESTER CARBONATES AND THEIR PREPARATION COVESTRO DEUTSCHLAND AG (DE) 2022-12-22 WO claimed
EP-2919782-A1 SECONDARY ALCOHOL SUBSITUTED TRIAZOLES AS PDE10 INHIBITORS Merck Sharp & Dohme Corp. (US) 2015-09-23 EP claimed
WO-2014078220-A1 SECONDARY ALCOHOL SUBSITUTED TRIAZOLES AS PDE10 INHIBITORS MERCK SHARP & DOHME CORP. (US) 2014-05-22 WO claimed
US-7510768-B2 Thermoplastic articles comprising cyclobutanediol having a decorative material embedded therein EASTMAN CHEMICAL COMPANY (US) 2009-03-31 US claimed
EP-1913053-A1 THERMOPLASTIC ARTICLES COMPRISING CYCLOBUTANEDIOL HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEMICAL COMPANY (US) 2008-04-23 EP claimed
WO-2007001571-A1 THERMOPLASTIC ARTICLES COMPRISING CYCLOBUTANEDIOL HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEMICAL COMPANY (US) 2007-01-04 WO claimed
US-20060286384-A1 Polyester/aromatic polycarbonate blend EASTMAN CHEMICAL COMPANY 2006-12-21 US claimed
EP-1569795-A1 THERMOPLASTIC ARTICLE HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEMICAL COMPANY (US) 2005-09-07 EP claimed
WO-2004048090-A1 THERMOPLASTIC ARTICLE HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEMICAL COMPANY (US) 2004-06-10 WO claimed
EP-1141113-A1 X-RAY CONTRASTING MOULDED PART WITH IMPROVED LONG-TERM STABILITY Bayer Aktiengesellschaft (DE) 2001-10-10 EP claimed
WO-2000037551-A1 X-RAY CONTRASTING MOULDED PART WITH IMPROVED LONG-TERM STABILITY BAYER AKTIENGESELLSCHAFT (DE) 2000-06-29 WO claimed
CN-118515537-B Modified divinylbenzene resin, preparation method and application thereof, thermosetting polymer material, and preparation method and application thereof 山东星顺新材料有限公司 2025-04-11 CN disclosed
EP-4381015-A1 POLYCARBONATE COMPOSITIONS HAVING A HIGH CTI Covestro Deutschland AG (DE) 2024-06-12 EP disclosed
EP-4355808-A1 OLIGOESTERS COMPRISING RESORCINOL AND ISO- AND/OR TEREPHTHALIC ACID, CORRESPONDING POLYESTER CARBONATES AND THEIR PREPARATION Covestro Deutschland AG (DE) 2024-04-24 EP disclosed
CN-117881739-A Composition and method for producing composition 株式会社钟化 2024-04-12 CN disclosed
EP-0034265-A2 Synergetically active mixtures of materials and their use in rendering polycarbonate moulding masses antistatic BAYER AG (DE) 1981-08-26 EP disclosed
EP-0028753-A1 Thermoplastic moulding masses from polycarbonate, polyolefin and a butadiene polymer BAYER AG (DE) 1981-05-20 EP disclosed
EP-0001578-A1 Modified polycarbonates and process for their preparation BAYER AG (DE) 1979-05-02 EP disclosed
EP-0001096-A2 Flame retardant polycarbonate blends Mobay Chemical Corporation (US) 1979-03-21 EP disclosed