Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 7/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4129742 | 0.84 | TRPV4 (0.39) | GAATRPV4CCR1PTGESATM | |
| SCHEMBL4134999 | 0.84 | GSTO1 (0.44) | GAATRPV4CCR1PTGDRPTGDR2 | |
| SCHEMBL4773183 | 0.83 | GAA (0.40) | GAATRPV4CCR1PTGESCNR1 | |
| SCHEMBL13872455 | 0.82 | ALDH1A1 (0.41) | GAATRPV4CCR1ALDH1A1 | |
| SCHEMBL4145503 | 0.81 | PTGES (0.41) | GAATRPV4PTGESPTGDRPTGDR2 | |
| SCHEMBL4136057 | 0.79 | GAA (0.40) | GAATRPV4CCR1PTGESCNR1 | |
| SCHEMBL4136813 | 0.79 | TRPV4 (0.40) | GAATRPV4CCR1PTGDRPTGDR2 | |
| SCHEMBL4136055 | 0.79 | GAA (0.40) | GAATRPV4CCR1PTGESCNR1 | |
| SCHEMBL4134996 | 0.79 | GAA (0.40) | GAATRPV4CCR1PTGDRPTGDR2 | |
| SCHEMBL4140486 | 0.79 | CCR1 (0.49) | CCR1CNR1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | SMITHKLINE BEECHAM CORPORATION | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | TRPV4, TRPC4, TRPV1 | GAA 3715/4885TRPV4 1/4885CCR1 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.