Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 6/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4136134 | 0.83 | GAA (0.41) | GAATRPV4CCR1FABP4CNR1 | |
| SCHEMBL4136057 | 0.82 | GAA (0.40) | GAATRPV4CCR1FABP4CNR1 | |
| SCHEMBL4136055 | 0.82 | GAA (0.40) | GAATRPV4CCR1FABP4CNR1 | |
| SCHEMBL4136813 | 0.82 | TRPV4 (0.40) | GAATRPV4CCR1PTGDRPTGDR2 | |
| SCHEMBL4134999 | 0.81 | GSTO1 (0.44) | GAATRPV4CCR1PTGDRPTGDR2 | |
| SCHEMBL4768147 | 0.80 | CCR1 (0.42) | GAATRPV4CCR1FABP4CNR1 | |
| SCHEMBL13872455 | 0.80 | ALDH1A1 (0.41) | GAATRPV4CCR1HPGD | |
| SCHEMBL4130382 | 0.79 | GAA (0.38) | GAATRPV4CCR1FABP4CNR1 | |
| SCHEMBL4130384 | 0.79 | GAA (0.38) | GAATRPV4CCR1FABP4CNR1 | |
| SCHEMBL4136390 | 0.79 | MAPK1 (0.40) | GAATRPV4CCR1FABP4PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940785-A2 | ACYCLIC 1,4-DIAMINES AND USES THEREOF | SmithKline Beecham Corporation (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007030761-A2 | ACYCLIC 1,4-DIAMINES AND USES THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-15 | — | — | WO | disclosed |