SCHEMBL4136722

SCHEMBL4136722

Nc1cccc2ccc[n+]([O-])c12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.43
TSHR P16473 3/20 0.43
ALDH1A1 P00352 3/20 0.43
HPGD P15428 3/20 0.43
HSD17B10 Q99714 2/20 0.43
KEAP1 Q14145 1/20 0.43
TDP1 Q9NUW8 3/20 0.39
KDM4E B2RXH2 4/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP2 O95551 1/20 0.38
NSD2 O96028 1/20 0.38
POLB P06746 1/20 0.38
THRB P10828 1/20 0.38
RECQL P46063 1/20 0.38
GALK1 P51570 1/20 0.38
BLM P54132 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HTT P42858 2/20 0.35
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5352485 0.79 MAPT (0.41) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL5894127 0.78 HSP90AA1 (0.36) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL29126971 0.77 MAPT (0.42) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL5894441 0.76 ALDH1A1 (0.40) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL2133978 0.74 CYP2A6 (0.43) TSHRALDH1A1HPGDHSD17B10TDP1
SCHEMBL21530568 0.74 MAPT (0.38) TDP1KDM4EMAPTKMT2ATDP2
SCHEMBL34468885 0.74 MAPT (0.43) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL3137043 0.74 CYP2A6 (0.43) TSHRTDP1KDM4EMAPTKMT2A
SCHEMBL100824 0.74 MAPT (0.43) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL6684284 0.73 ALDH1A1 (0.50) TSHRALDH1A1HPGDHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111058069-A Plating solution for electroplating tin alloy 上村工业株式会社 2020-04-24 CN claimed
US-20200123673-A1 ELECTROLYTIC TIN ALLOY PLATING SOLUTION C. UYEMURA & CO., LTD. (JP) 2020-04-23 US claimed
US-20250099488-A1 ANTI-PARASITE COMPOUNDS AUSTRALIAN NATIONAL UNIVERSITY (AU) 2025-03-27 US disclosed
EP-4469058-A1 ANTI-PARASITE COMPOUNDS Australian National University (AU) 2024-12-04 EP disclosed
WO-2023137529-A1 ANTI-PARASITE COMPOUNDS AUSTRALIAN NATIONAL UNIVERSITY (AU) 2023-07-27 WO disclosed
US-20230128322-A1 SYK KINASE INHIBITORS AS TREATMENT FOR MALARIA PURDUE RESEARCH FOUNDATION 2023-04-27 US disclosed
US-20200345737-A1 SYK KINASE INHIBITORS AS TREATMENT FOR MALARIA PURDUE RESEARCH FOUNDATION 2020-11-05 US disclosed
WO-2020107189-A1 PYRROLIDINE COMPOUNDS FOR THE TREATMENT OF MALARIA LEGION PHARMA CO. LTD (CN) 2020-06-04 WO disclosed
CN-111058069-A Plating solution for electroplating tin alloy 上村工业株式会社 2020-04-24 CN disclosed
US-20200123673-A1 ELECTROLYTIC TIN ALLOY PLATING SOLUTION C. UYEMURA & CO., LTD. (JP) 2020-04-23 US disclosed
US-9701637-B2 Tau imaging probe GE HEALTHCARE LIMITED (GB) 2017-07-11 US disclosed
US-20140309233-A1 SYK KINASE INHIBITORS AS TREATMENT FOR MALARIA HULOW, LLC (US) 2014-10-16 US disclosed
US-20140296532-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF MALARIA GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) 2014-10-02 US disclosed
WO-2014160775-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF MALARIA SAINT LOUIS UNIVERSITY (US) 2014-10-02 WO disclosed
WO-2014100113-A2 SYK KINASE INHIBITORS AS TREATMENT FOR MALARIA HULOW, LLC (US) 2014-06-26 WO disclosed
US-20140100178-A1 COMPOSITION AND METHODS FOR SITE-SPECIFIC DRUG DELIVERY TO TREAT MALARIA AND OTHER LIVER DISEASES ANSARI ASLAM (US) 2014-04-10 US disclosed
EP-2188259-B1 QUINOLINE DERIVATIVES AS ANTI-CANCER AGENTS UNIV HONG KONG POLYTECHNIC (CN) 2013-11-06 EP disclosed
EP-2634177-A1 TAU IMAGING PROBE Clino Ltd. (JP) 2013-09-04 EP disclosed
US-20090054482-A1 Method of making and administering quinoline derivatives as anti-cancer agents THE HONG KONG POLYTECHNIC UNIVERSITY (HK) 2009-02-26 US disclosed
US-5837289-A ORGANOGEL COMPRISING FATTY ACID PHOSPHOLIPID EMULSIFYING AGENT AND FATTY ACID OR ESTER THEREOF IMPRIMIS PHARMACEUTICALS, INC. 1998-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128322-A1 SYK KINASE INHIBITORS AS TREATMENT FOR MALARIA SYK, BTK, MERTK CYP3A4 4082/4885TSHR 4179/4885ALDH1A1 4131/4885
US-20250099488-A1 ANTI-PARASITE COMPOUNDS TUBA3C, CFAP20, CFAP410 CYP3A4 3433/4885TSHR 4563/4885ALDH1A1 1357/4885
US-20140309233-A1 SYK KINASE INHIBITORS AS TREATMENT FOR MALARIA SYK, BTK, MERTK CYP3A4 4082/4885TSHR 4179/4885ALDH1A1 4131/4885
US-20140100178-A1 COMPOSITION AND METHODS FOR SITE-SPECIFIC DRUG DELIVERY TO TREAT MALARIA AND OTHER LIVER DISEASES HEXD, LCT, PYGL CYP3A4 256/4885TSHR 3769/4885ALDH1A1 457/4885
US-20140296532-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF MALARIA BACE2, DNPEP, ACE CYP3A4 749/4885TSHR 4876/4885ALDH1A1 1822/4885
US-20090054482-A1 Method of making and administering quinoline derivatives as anti-cancer agents HCCS, GLS2, NQO1 CYP3A4 172/4885TSHR 4295/4885ALDH1A1 959/4885
US-20200345737-A1 SYK KINASE INHIBITORS AS TREATMENT FOR MALARIA SYK, BTK, MERTK CYP3A4 4082/4885TSHR 4179/4885ALDH1A1 4131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.