Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4153261 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2RAB9AHPGDMAPTKMT2A | |
| SCHEMBL13872428 | 0.77 | SMN1; SMN2 (0.45) | HTR7SMN1; SMN2RAB9AHPGDMAPT | |
| SCHEMBL2961408 | 0.73 | ALDH1A1 (0.65) | HTR7SMN1; SMN2RAB9AHPGDMAPT | |
| SCHEMBL8072110 | 0.71 | ALDH1A1 (0.44) | SMN1; SMN2HPGDMAPTKMT2ALMNA | |
| SCHEMBL6923951 | 0.70 | MAOB (0.47) | SMN1; SMN2RAB9AMAPTNPC1KMT2A | |
| SCHEMBL31454232 | 0.70 | FGFR1 (0.41) | RAB9AGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5651714 | 0.68 | ALDH1A1 (0.57) | SMN1; SMN2MAPTKMT2AALDH1A1PTPN1 | |
| SCHEMBL3490759 | 0.68 | HSP90AA1 (0.50) | HTR7SMN1; SMN2RAB9AHPGDMAPT | |
| SCHEMBL6298933 | 0.68 | KMT2A (0.51) | SMN1; SMN2HPGDMAPTKMT2ALMNA | |
| SCHEMBL498267 | 0.67 | KDM4E (0.54) | SMN1; SMN2RAB9AHPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090093476-A1 | PYRROLO[1,2-A]QUINOXALINE DERIVATIVES AS ADENOSINE A3 RECEPTOR MODULATORS AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2009-04-09 | — | — | US | disclosed |
| EP-1973916-A1 | PYRROLO Ýl,2-A¨QUINOXALINE DERIVATIVES AS ADENOSINE A3 RECEPTOR MODULATORS AND USES THEREOF | Faust Pharmaceuticals (FR) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007071379-A1 | PYRROLO [l,2-A]QUINOXALINE DERIVATIVES AS ADENOSINE A3 RECEPTOR MODULATORS AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2007-06-28 | — | — | WO | disclosed |
| EP-1798233-A1 | Pyrrolo[1,2-a]quinoxaline derivatives as Adenosine A3 receptor modulators and uses thereof | Faust Pharmaceuticals (FR) | 2007-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093476-A1 | PYRROLO[1,2-A]QUINOXALINE DERIVATIVES AS ADENOSINE A3 RECEPTOR MODULATORS AND USES THEREOF | ADORA3, ADORA2A, ADORA1 | HTR7 379/4885SMN1; SMN2 4266/4885RAB9A 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.