SCHEMBL4137984

SCHEMBL4137984

COCOc1cc(C=O)cc(OCOC)c1OCOC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.43
ALDH1A1 P00352 10/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 4/20 0.40
TDP1 Q9NUW8 2/20 0.38
TRIM24 O15164 1/20 0.38
HPGD P15428 1/20 0.38
ALDH5A1 P51649 1/20 0.38
ABAT P80404 1/20 0.38
TRIM33 Q9UPN9 1/20 0.38
KDM4E B2RXH2 1/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
MAPT P10636 4/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27944694 0.95 ALDH1A1 (0.48) FDPSALDH1A1TSHRMAPK1L3MBTL1
SCHEMBL30875129 0.95 ALDH1A1 (0.48) FDPSALDH1A1TSHRMAPK1L3MBTL1
SCHEMBL2744767 0.91 ALDH1A1 (0.50) FDPSALDH1A1TSHRMAPK1L3MBTL1
SCHEMBL31471641 0.91 FDPS (0.46) FDPSALDH1A1TSHRMAPK1L3MBTL1
SCHEMBL23202773 0.88 ALDH1A1 (0.56) FDPSALDH1A1TSHRMAPK1L3MBTL1
SCHEMBL7680122 0.88 ALDH1A1 (0.44) FDPSALDH1A1TSHRMAPK1L3MBTL1
SCHEMBL3123095 0.87 FDPS (0.41) FDPSALDH1A1TSHRMAPK1L3MBTL1
SCHEMBL13116218 0.84 SRC (0.42) FDPSALDH1A1TSHRMAPK1L3MBTL1
SCHEMBL7951806 0.84 FDPS (0.41) FDPSALDH1A1TSHRMAPK1L3MBTL1
SCHEMBL21722590 0.83 ALDH1A1 (0.46) FDPSALDH1A1TSHRMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116514759-A Synthesis method of dihydromyricetin 华中农业大学 2023-08-01 CN claimed
CN-116514759-A Synthesis method of dihydromyricetin 华中农业大学 2023-08-01 CN disclosed
US-11643405-B2 Compound for treatment or prevention of liver diseases JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) 2023-05-09 US disclosed
US-11643405-B2 Compound for treatment or prevention of liver diseases JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) 2023-05-09 US disclosed
CN-110183431-B Compound for treating or preventing liver diseases 江苏新元素医药科技有限公司 2023-04-11 CN disclosed
US-20210246126-A1 COMPOUND FOR TREATMENT OR PREVENTION OF LIVER DISEASES JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) 2021-08-12 US disclosed
EP-3805216-A1 COMPOUNDS FOR TREATMENT OR PREVENTION OF LIVER DISEASES Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd. (CN) 2021-04-14 EP disclosed
US-20090092624-A1 Antiinfective Flavononol Compounds and Methods of Use Thereof HERBALSCIENCE GROUP, LLC 2009-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210246126-A1 COMPOUND FOR TREATMENT OR PREVENTION OF LIVER DISEASES SLC10A1, GYS2, CPT1A FDPS 203/4885ALDH1A1 164/4885TSHR 2573/4885
US-20090092624-A1 Antiinfective Flavononol Compounds and Methods of Use Thereof MPO, VIP, FABP2 FDPS 147/4885ALDH1A1 894/4885TSHR 4811/4885
US-11643405-B2 Compound for treatment or prevention of liver diseases SLC10A1, GYS2, CPT1A FDPS 203/4885ALDH1A1 164/4885TSHR 2573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.