SCHEMBL3123095

SCHEMBL3123095

COCOc1cc(C=O)cc(OCOC)c1OCCF

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.41
APP P05067 2/20 0.38
ALDH1A1 P00352 11/20 0.36
MAPK1 P28482 2/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
TSHR P16473 1/20 0.35
TNFRSF1A P19438 1/20 0.35
MAPT P10636 5/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HPGD P15428 4/20 0.33
TDP1 Q9NUW8 2/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
ALOX12 P18054 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
TRIM24 O15164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4137984 0.87 FDPS (0.43) FDPSALDH1A1MAPK1L3MBTL1TSHR
SCHEMBL27944694 0.82 ALDH1A1 (0.48) FDPSALDH1A1MAPK1L3MBTL1TSHR
SCHEMBL30875129 0.82 ALDH1A1 (0.48) FDPSALDH1A1MAPK1L3MBTL1TSHR
SCHEMBL31471641 0.82 FDPS (0.46) FDPSALDH1A1MAPK1L3MBTL1TSHR
SCHEMBL2744767 0.78 ALDH1A1 (0.50) FDPSALDH1A1MAPK1L3MBTL1TSHR
SCHEMBL23202773 0.76 ALDH1A1 (0.56) FDPSALDH1A1MAPK1L3MBTL1TSHR
SCHEMBL7951806 0.76 FDPS (0.41) FDPSALDH1A1MAPK1L3MBTL1TSHR
SCHEMBL7680122 0.76 ALDH1A1 (0.44) FDPSALDH1A1MAPK1L3MBTL1TSHR
SCHEMBL13116218 0.76 SRC (0.42) FDPSALDH1A1MAPK1L3MBTL1TSHR
SCHEMBL3125765 0.76 MEN1 (0.43) ALDH1A1L3MBTL1TSHRTNFRSF1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12324845-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2025-06-10 US disclosed
US-20250161500-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-22 US disclosed
US-20220288243-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2022-09-15 US disclosed
US-11241509-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2022-02-08 US disclosed
US-11241509-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2022-02-08 US disclosed
EP-2474525-B1 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING INC (US) 2020-04-15 EP disclosed
EP-2474523-B1 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING INC (US) 2020-04-08 EP disclosed
US-20180339070-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2018-11-29 US disclosed
US-10010631-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2018-07-03 US disclosed
US-10010631-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2018-07-03 US disclosed
EP-2474526-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 EP disclosed
EP-2474526-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 EP disclosed
EP-2474523-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 EP disclosed
EP-2474525-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 EP disclosed
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION CITIZENS BANK, N.A. 2010-09-02 US disclosed
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION CITIZENS BANK, N.A. 2010-09-02 US disclosed
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION CITIZENS BANK, N.A. 2010-09-02 US disclosed
EP-2114873-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION Lantheus Medical Imaging, Inc. (US) 2009-11-11 EP disclosed
WO-2008083056-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2008-07-10 WO disclosed
WO-2008083056-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2008-07-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10010631-B2 Ligands for imaging cardiac innervation TNNT2, PNMT, TNNC1 FDPS 4136/4885APP 2683/4885ALDH1A1 798/4885
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 FDPS 4136/4885APP 2683/4885ALDH1A1 798/4885
US-20180339070-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 FDPS 4136/4885APP 2683/4885ALDH1A1 798/4885
US-20220288243-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 FDPS 4136/4885APP 2683/4885ALDH1A1 798/4885
US-11241509-B2 Ligands for imaging cardiac innervation TNNT2, PNMT, TNNC1 FDPS 4105/4885APP 2703/4885ALDH1A1 662/4885
US-20250161500-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 FDPS 4136/4885APP 2683/4885ALDH1A1 798/4885
US-12324845-B2 Ligands for imaging cardiac innervation CHRNB4, RXFP4, RXFP3 FDPS 4218/4885APP 3739/4885ALDH1A1 3732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.