Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159635 | 0.86 | MAPK1 (1.00) | MAPK1MAPTPKMRAB9ANPSR1 | |
| Hydrochloric Acid SCHEMBL11102389 | 0.85 | MAPK1 (0.97) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL8884292 | 0.81 | MAPK1 (0.77) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL28058849 | 0.80 | MAPT (0.49) | MAPK1MAPTPKMRAB9AKMT2A | |
| SCHEMBL7014000 | 0.80 | MAPK1 (0.82) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL6161561 | 0.79 | MAPK1 (0.80) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL6585695 | 0.78 | MAPK1 (0.78) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL4069632 | 0.78 | MEN1 (0.76) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL3288703 | 0.78 | MAPK1 (0.78) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL3604839 | 0.78 | MAPK1 (0.74) | MAPK1MAPTPKMRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | PFIZER INC | 2009-08-20 | — | — | US | disclosed |
| US-20090209578-A1 | CHEMICAL COMPOUNDS | PFIZER INC | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CXCR1 | MAPK1 1254/4885MAPT 4495/4885PKM 1912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.