SCHEMBL4139032

SCHEMBL4139032

CCOC(=O)C1CC1c1ccc2ccccc2c1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 6/20 0.48
SLC6A3 Q01959 4/20 0.48
HCAR2 Q8TDS4 1/20 0.46
SLC6A2 P23975 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4139034 1.00 SLC6A4 (0.48) SLC6A4SLC6A3HCAR2SLC6A2
SCHEMBL3596278 0.82 ALOX15 (0.43)
SCHEMBL2136550 0.82 ALDH1A1 (0.41)
SCHEMBL2136544 0.82 ALDH1A1 (0.41)
SCHEMBL4135351 0.82 MAPT (0.62)
SCHEMBL14270533 0.82 MAPT (0.62)
SCHEMBL4129635 0.82 MAPT (0.62)
SCHEMBL12908203 0.82 MAPT (0.62)
SCHEMBL12706756 0.82 MAPT (0.62)
SCHEMBL12908208 0.82 MAPT (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3782977-A1 CYCLOPROPANATION METHOD AND REAGENT Fundació Privada Institut Català d'Investigació Química (ICIQ) (ES) 2021-02-24 EP disclosed
US-20090203750-A1 5-HT2C Receptor Agonists as Anorectic Agents NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-08-13 US disclosed
WO-2007025144-A1 5-HT2C RECEPTOR AGONISTS AS ANORECTIC AGENTS UNIVERSITY OF ILLINOIS - CHICAGO (US) 2007-03-01 WO disclosed
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2006-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes PPOX, HCCS, ICOSLG SLC6A4 4568/4885SLC6A3 4575/4885HCAR2 882/4885
US-20090203750-A1 5-HT2C Receptor Agonists as Anorectic Agents HTR2C, HTR2A, HTR5A SLC6A4 55/4885SLC6A3 181/4885HCAR2 22/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.