Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Eprosartan. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 known ✓ | P30556 | 2/20 | 0.92 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.92 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.92 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eprosartan SCHEMBL5785067 | 1.00 | AGTR1 (0.92) | AGTR1ABCC3ABCC2 | |
| Eprosartan SCHEMBL41397 | 1.00 | AGTR1 (0.92) | AGTR1ABCC3ABCC2 | |
| Eprosartan SCHEMBL3972893 | 1.00 | AGTR1 (0.92) | AGTR1ABCC3ABCC2 | |
| Eprosartan SCHEMBL1504815 | 0.99 | AGTR1 (0.91) | AGTR1ABCC3ABCC2 | |
| Eprosartan SCHEMBL4382102 | 0.99 | AGTR1 (0.91) | AGTR1ABCC3ABCC2 | |
| Eprosartan SCHEMBL1504814 | 0.99 | AGTR1 (0.91) | AGTR1ABCC3ABCC2 | |
| Eprosartan SCHEMBL4382107 | 0.99 | AGTR1 (0.91) | AGTR1ABCC3ABCC2 | |
| Eprosartan SCHEMBL74813 | 0.97 | AGTR1 (0.92) | AGTR1ABCC3ABCC2 | |
| Eprosartan SCHEMBL156290 | 0.96 | AGTR1 (1.00) | AGTR1ABCC3ABCC2 | |
| Eprosartan SCHEMBL1815060 | 0.96 | AGTR1 (1.00) | AGTR1ABCC3ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5302 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122088499-A | Biomedical relation extraction method and system based on difficult sample perception | — | 2026-05-26 | — | — | CN | claimed |
| CN-120331769-B | Auger mining robot and self-adaptive cutting control method | CHINA UNIVERSITY OF MINING AND TECHNOLOGY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-116959482-B | Musical instrument tone color conversion method based on time-frequency characteristic refinement | 华南理工大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122017631-A | Method for determining state of charge of battery | 固德威技术股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| WO-2025131019-A1 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF INHIBIN SUBUNIT BETA E (INHBE) | SHANGHAI ARGO BIOPHARMACEUTICAL CO., LTD. (CN) | 2025-06-26 | — | — | WO | claimed |
| CN-120196122-A | Compound control method for wind interference resistance of four-rotor unmanned aerial vehicle | 北方工业大学 | 2025-06-24 | — | — | CN | claimed |
| CN-120165441-A | Cooperation scheduling operation method and device for multi-level power system of national network province | 清华四川能源互联网研究院 | 2025-06-17 | — | — | CN | claimed |
| CN-117767266-B | Electric automobile cluster charging regulation and control method in electric power market | 国网智慧车联网技术有限公司 | 2025-06-17 | — | — | CN | claimed |
| CN-119712531-B | Method and system for monitoring operation state of aviation main pump verification test bed | 西安康创电子科技有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-119987191-A | Closed loop optimization method for cerebral apoplexy electrical stimulation treatment | 济南大学 | 2025-05-13 | — | — | CN | claimed |
| WO-1999045779-A1 | NOVEL COMPOSITIONS OF EPROSARTAN | SMITHKLINE BEECHAM CORPORATION (US) | 1999-09-16 | — | — | WO | claimed |
| EP-0889880-A4 | EPROSARTAN DIHYDRATE AND A PROCESS FOR ITS PRODUCTION AND FORMULATION | SMITHKLINE BEECHAM CORP (US) | 1999-06-23 | — | — | EP | claimed |
| EP-0565634-B1 | ANGIOTENSIN II RECEPTOR BLOCKING COMPOSITIONS | SMITHKLINE BEECHAM CORP (US) | 1999-03-17 | — | — | EP | claimed |
| EP-0889880-A1 | EPROSARTAN DIHYDRATE AND A PROCESS FOR ITS PRODUCTION AND FORMULATION | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-13 | — | — | EP | claimed |
| WO-1997036874-A1 | EPROSARTAN DIHYDRATE AND A PROCESS FOR ITS PRODUCTION AND FORMULATION | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-09 | — | — | WO | claimed |
| US-5656650-A | TREATING HYPERTENSION | SMITHKLINE BEECHAM CORP. | 1997-08-12 | — | — | US | claimed |
| EP-0565634-A1 | ANGIOTENSIN II RECEPTOR BLOCKING COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-20 | — | — | EP | claimed |
| WO-1993006828-A1 | MEDICAMENT FOR THE TREATMENT OF ANXIETY | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-15 | — | — | WO | claimed |
| US-5185351-A | Hypotensive agents; for treatment of congestive heart failure, renal failure and glaucoma | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-09 | — | — | US | claimed |
| WO-1992010097-A1 | ANGIOTENSIN II RECEPTOR BLOCKING COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-06-25 | — | — | WO | claimed |