Eprosartan

Eprosartan

SCHEMBL41397

CCCCc1ncc(C=C(Cc2cccs2)C(=O)O)n1Cc1ccc(C(=O)O)cc1.CS(=O)(=O)O

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1

The experimentally established mechanism targets of Eprosartan. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AGTR1 known ✓ P30556 2/20 0.92
ABCC3 O15438 1/20 0.92
ABCC2 Q92887 1/20 0.92

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eprosartan SCHEMBL5785067 1.00 AGTR1 (0.92) AGTR1ABCC3ABCC2
Eprosartan SCHEMBL3972893 1.00 AGTR1 (0.92) AGTR1ABCC3ABCC2
Eprosartan SCHEMBL41396 1.00 AGTR1 (0.92) AGTR1ABCC3ABCC2
Eprosartan SCHEMBL1504815 0.99 AGTR1 (0.91) AGTR1ABCC3ABCC2
Eprosartan SCHEMBL4382102 0.99 AGTR1 (0.91) AGTR1ABCC3ABCC2
Eprosartan SCHEMBL1504814 0.99 AGTR1 (0.91) AGTR1ABCC3ABCC2
Eprosartan SCHEMBL4382107 0.99 AGTR1 (0.91) AGTR1ABCC3ABCC2
Eprosartan SCHEMBL74813 0.97 AGTR1 (0.92) AGTR1ABCC3ABCC2
Eprosartan SCHEMBL156290 0.96 AGTR1 (1.00) AGTR1ABCC3ABCC2
Eprosartan SCHEMBL1815060 0.96 AGTR1 (1.00) AGTR1ABCC3ABCC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2797 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025131019-A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF INHIBIN SUBUNIT BETA E (INHBE) SHANGHAI ARGO BIOPHARMACEUTICAL CO., LTD. (CN) 2025-06-26 WO claimed
US-20240252528-A1 Methods Of Treating Metabolic Disorders And Cardiovascular Disease With Inhibin Subunit Beta E (INHBE) Inhibitors REGENERON PHARMACEUTICALS, INC. 2024-08-01 US claimed
CN-118325376-A Antimicrobial coating and preparation method and application thereof 泛领生物医学技术(苏州)有限公司 2024-07-12 CN claimed
EP-3737676-B1 ACETAL COMPOUNDS AND THERAPEUTIC USES THEREOF LIGAND PHARM INC (US) 2024-03-06 EP claimed
US-11851443-B2 Neprilysin inhibitors THERAVANCE BIOPHARMA R&D IP, LLC (US) 2023-12-26 US claimed
EP-4259279-A1 METHODS OF TREATING METABOLIC DISORDERS AND CARDIOVASCULAR DISEASE WITH INHIBIN SUBUNIT BETA E (INHBE) INHIBITORS REGENERON PHARMACEUTICALS, INC. (US) 2023-10-18 EP claimed
US-11718591-B2 Crystalline (2S,4R)-5-(5′-chloro-2′-fluoro-[1,1′-biphenyl]-4-yl)-2-(ethoxymethyl)-4-(3-hydroxyisoxazole-5-carboxamido)-2- methylpentanoic acid and uses thereof THERAVANCE BIOPHARMA R&D IP, LLC (US) 2023-08-08 US claimed
US-20230017661-A1 COMPOSITIONS AND MODULAR NANO- AND MICROPARTICLES FOR THE DELIVERY OF VARIOUS AGENTS AND USE THEREOF VERI NANO INC. (US) 2023-01-19 US claimed
US-20220313726-A1 Methods Of Treating Metabolic Disorders And Cardiovascular Disease With Inhibin Subunit Beta E (INHBE) Inhibitors REGENERON PHARMACEUTICALS, INC. 2022-10-06 US claimed
US-20220298173-A1 NEPRILYSIN INHIBITORS THERAVANCE BIOPHARMA R&D IP, LLC (US) 2022-09-22 US claimed
EP-0660713-B1 USE OF ANGIOTENSIN II ANTAGONISTS IN THE TREATMENT OF LEFT VENTRICULAR HYPERTROPHY SMITHKLINE BEECHAM PLC (GB) 2001-10-24 EP claimed
EP-1098634-A2 BIOENHANCED FORMULATIONS COMPRISING EPROSARTAN IN ORAL SOLID DOSAGE FORM SmithKline Beecham Corporation (US) 2001-05-16 EP claimed
EP-1061803-A1 NOVEL COMPOSITIONS OF EPROSARTAN SMITHKLINE BEECHAM CORPORATION (US) 2000-12-27 EP claimed
WO-2000053282-A1 CRYSTALLIZATION PROCESS FOR PRODUCING FINE CRYSTAL PRODUCTS SMITHKLINE BEECHAM P.L.C. (GB) 2000-09-14 WO claimed
WO-2000004862-A2 BIOENHANCED FORMULATIONS COMPRISING EPROSARTAN IN ORAL SOLID DOSAGE FORM SMITHKLINE BEECHAM CORPORATION (US) 2000-02-03 WO claimed
WO-1999045779-A1 NOVEL COMPOSITIONS OF EPROSARTAN SMITHKLINE BEECHAM CORPORATION (US) 1999-09-16 WO claimed
EP-0565634-B1 ANGIOTENSIN II RECEPTOR BLOCKING COMPOSITIONS SMITHKLINE BEECHAM CORP (US) 1999-03-17 EP claimed
US-5656650-A TREATING HYPERTENSION SMITHKLINE BEECHAM CORP. 1997-08-12 US claimed
WO-1993006828-A1 MEDICAMENT FOR THE TREATMENT OF ANXIETY SMITHKLINE BEECHAM CORPORATION (US) 1993-04-15 WO claimed
US-5185351-A Hypotensive agents; for treatment of congestive heart failure, renal failure and glaucoma SMITHKLINE BEECHAM CORPORATION (US) 1993-02-09 US claimed