Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | PRKDC | P78527 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 5/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5643949 | 0.84 | ALOX15 (0.62) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL16117692 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL10333651 | 0.80 | HPGD (0.58) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL92809 | 0.79 | CYP3A4 (0.64) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL13939800 | 0.77 | ALOX15 (0.68) | ALDH1A1KDM4ELMNACYP3A4ALOX15 | |
| SCHEMBL398164 | 0.76 | CYP3A4 (0.74) | ALDH1A1KDM4ELMNACYP3A4ALOX15 | |
| SCHEMBL5698339 | 0.74 | ALDH1A1 (0.81) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL3136850 | 0.74 | ALDH1A1 (0.90) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL17821658 | 0.73 | HPGD (0.53) | ALDH1A1KDM4ELMNAHPGDMAPT | |
| SCHEMBL21455229 | 0.73 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655307-A1 | COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS | Givaudan SA (CH) | 2013-10-30 | — | — | EP | claimed |
| WO-2012085287-A1 | COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS | GIVAUDAN SA (CH) | 2012-06-28 | — | — | WO | claimed |
| US-20090238785-A1 | Novel Aldehydic Musks and Derivatives Thereof | FLEXITRAL, INC. (US) | 2009-09-24 | — | — | US | claimed |
| CN-101184744-A | Aroma precursor and flavor precursor composition | FLEXITRAL INC (US) | 2008-05-21 | — | — | CN | claimed |
| EP-1848702-A2 | PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS | Flexitral, Inc. (US) | 2007-10-31 | — | — | EP | claimed |
| EP-1771540-A4 | NOVEL ALDEHYDIC MUSKS AND DERIVATIVES THEREOF | FLEXITRAL INC (US) | 2007-09-12 | — | — | EP | claimed |
| CN-1993454-A | Novel aldehydic musks and derivatives thereof | FLEXITRAL INC (US) | 2007-07-04 | — | — | CN | claimed |
| EP-1771540-A1 | NOVEL ALDEHYDIC MUSKS AND DERIVATIVES THEREOF | Flexitral, Inc. (US) | 2007-04-11 | — | — | EP | claimed |
| US-20060205632-A1 | Pro-fragrance and pro-flavorant compositions | FLEXITRAL, INC. | 2006-09-14 | — | — | US | claimed |
| WO-2006085048-A2 | PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS | FLEXITRAL, INC. (US) | 2006-08-17 | — | — | WO | claimed |
| WO-2006012215-A1 | NOVEL ALDEHYDIC MUSKS AND DERIVATIVES THEREOF | FLEXITRAL, INC. (US) | 2006-02-02 | — | — | WO | claimed |
| EP-2655307-A1 | COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS | Givaudan SA (CH) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012085287-A1 | COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS | GIVAUDAN SA (CH) | 2012-06-28 | — | — | WO | disclosed |
| US-20090238785-A1 | Novel Aldehydic Musks and Derivatives Thereof | FLEXITRAL, INC. (US) | 2009-09-24 | — | — | US | disclosed |
| US-20090238785-A1 | Novel Aldehydic Musks and Derivatives Thereof | FLEXITRAL, INC. (US) | 2009-09-24 | — | — | US | disclosed |
| US-20060205632-A1 | Pro-fragrance and pro-flavorant compositions | FLEXITRAL, INC. | 2006-09-14 | — | — | US | disclosed |
| WO-2006085048-A2 | PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS | FLEXITRAL, INC. (US) | 2006-08-17 | — | — | WO | disclosed |
| WO-2006012215-A1 | NOVEL ALDEHYDIC MUSKS AND DERIVATIVES THEREOF | FLEXITRAL, INC. (US) | 2006-02-02 | — | — | WO | disclosed |
| US-4774076-A | DENTIFRICES, MOUTHWASHES | LION CORPORATION (JP) | 1988-09-27 | — | — | US | disclosed |
| US-4649044-A | DISCOLORATION INHIBITION | LION CORPORATION (JP) | 1987-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238785-A1 | Novel Aldehydic Musks and Derivatives Thereof | ALDH2, ME2, ALDH3A1 | ALDH1A1 11/4885KDM4E 1020/4885TSHR 4437/4885 |
| US-20060205632-A1 | Pro-fragrance and pro-flavorant compositions | TAS2R10, TAS2R9, OR10J3 | ALDH1A1 1201/4885KDM4E 2618/4885TSHR 2205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.