SCHEMBL4144646

SCHEMBL4144646

CC(=O)OC(=O)C=CC(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29911001 0.87 KEAP1 (0.35) ALDH1A1TSHRKEAP1NFE2L2HCAR2
SCHEMBL23600903 0.79
SCHEMBL230634 0.79 ALDH1A1 (0.67) ALDH1A1TSHRHSD17B10TDP1KEAP1
SCHEMBL825979 0.79 ALDH1A1 (0.67) ALDH1A1TSHRHSD17B10TDP1KEAP1
SCHEMBL14152614 0.79 ALDH1A1 (0.67) ALDH1A1TSHRHSD17B10TDP1KEAP1
SCHEMBL22734018 0.76 ELANE (0.32)
SCHEMBL1881404 0.75 NFE2L2 (0.60) ALDH1A1HSD17B10TDP1KEAP1NFE2L2
SCHEMBL3022767 0.75 NFE2L2 (0.60) ALDH1A1HSD17B10TDP1KEAP1NFE2L2
Acetic Acid SCHEMBL29018083 0.74 ALDH1A1 (0.59) ALDH1A1TSHRHSD17B10TDP1KEAP1
SCHEMBL18960907 0.73 KEAP1 (0.32) KEAP1NFE2L2HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090130419-A1 FOAM SHEET AND PRODUCTION PROCESS THEREOF OJI PAPER CO., LTD (JP) 2009-05-21 US disclosed
US-20060210785-A1 Foamed product in a sheet form and method for production thereof OJI PAPER CO., LTD. (JP) 2006-09-21 US disclosed
EP-1647570-A1 FOAMED PRODUCT IN A SHEET FORM AND METHOD FOR PRODUCTION THEREOF Oji Paper Co., Ltd. (JP) 2006-04-19 EP disclosed