Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10751518 | 0.82 | PTPN11 (0.56) | PTPN11PTGER1MAPK1KMT2AALDH1A1 | |
| Hydroquinone SCHEMBL8945656 | 0.77 | LTA4H (0.44) | PTPN11KMT2AALDH1A1TP53PDE10A | |
| SCHEMBL4154550 | 0.75 | PTPN11 (0.49) | PTPN11PTGER1MAPK1KMT2AALDH1A1 | |
| SCHEMBL124950 | 0.75 | ALDH1A1 (0.71) | PTPN11KMT2AALDH1A1PTK2BMEN1 | |
| SCHEMBL31643582 | 0.75 | ALDH1A1 (0.71) | PTPN11KMT2AALDH1A1PTK2BMEN1 | |
| SCHEMBL10750541 | 0.75 | PTPN11 (0.64) | PTPN11PTGER1MAPK1KMT2AALDH1A1 | |
| Bicarbonate SCHEMBL236595 | 0.74 | ALDH1A1 (0.69) | PTPN11KMT2AALDH1A1PTK2BMEN1 | |
| Bicarbonate SCHEMBL21753663 | 0.74 | ALDH1A1 (0.69) | PTPN11KMT2AALDH1A1PTK2BMEN1 | |
| Bicarbonate SCHEMBL29943695 | 0.74 | ALDH1A1 (0.69) | PTPN11KMT2AALDH1A1PTK2BMEN1 | |
| SCHEMBL28219872 | 0.74 | ALDH1A1 (0.69) | PTPN11KMT2AALDH1A1PTK2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090030218-A1 | Method For Producing Aminoalcohol Derivative Having Biphenyl Group | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-01-29 | — | — | US | claimed |
| EP-1932826-A1 | METHOD FOR PRODUCING AMINOALCOHOL DERIVATIVE HAVING BIPHENYL GROUP | Kissei Pharmaceutical Co., Ltd. (JP) | 2008-06-18 | — | — | EP | claimed |
| US-20090030218-A1 | Method For Producing Aminoalcohol Derivative Having Biphenyl Group | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1932826-A1 | METHOD FOR PRODUCING AMINOALCOHOL DERIVATIVE HAVING BIPHENYL GROUP | Kissei Pharmaceutical Co., Ltd. (JP) | 2008-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030218-A1 | Method For Producing Aminoalcohol Derivative Having Biphenyl Group | ALDH7A1, DDC, ADH5 | PTPN11 3466/4885PTGER1 3154/4885MAPK1 4175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.