Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RGS4 | P49798 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | RGS8 | P57771 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196320 | 0.95 | ADORA2B (0.49) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL4150749 | 0.86 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL4146852 | 0.83 | TDP1 (0.40) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL4146972 | 0.79 | ADORA2B (0.40) | ADORA2BTDP1 | |
| SCHEMBL19147865 | 0.77 | ALDH1A1 (0.53) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL19147853 | 0.77 | ALDH1A1 (0.53) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL19148089 | 0.77 | ALDH1A1 (0.53) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL27700732 | 0.75 | RGS4 (0.42) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL10656238 | 0.75 | ALDH1A1 (0.52) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL4152333 | 0.75 | TDP1 (0.41) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048374-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | BAERLOCHER GMBH (DE) | 2009-02-19 | — | — | US | disclosed |
| EP-1996649-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | Baerlocher GmbH (DE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007104379-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | BAERLOCHER GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |