Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28868937 | 0.79 | RECQL (0.60) | RECQLMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5914151 | 0.78 | RECQL (0.58) | RECQLMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6886838 | 0.78 | COMT (0.68) | RECQLNPY5RSCN2ANPC1RAB9A | |
| SCHEMBL25270517 | 0.78 | RECQL (0.63) | RECQLMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5371995 | 0.76 | SCN2A (0.61) | RECQLMEN1KMT2AALDH1A1NPY5R | |
| SCHEMBL11666314 | 0.76 | PIN1 (0.54) | RECQLMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11422025 | 0.75 | PIN1 (0.62) | RECQLNPY5RSCN2APIN1KDM4E | |
| SCHEMBL15614429 | 0.74 | RECQL (1.00) | RECQLKMT2AHPGDSMN1; SMN2NPY5R | |
| SCHEMBL3521755 | 0.74 | RECQL (0.54) | RECQLMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1163852 | 0.73 | RECQL (0.53) | RECQLKMT2AALDH1A1NPY5RSCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005560-A1 | PRODUCTION METHOD OF DIAMINOPYRIMIDINE COMPOUNDS | AJINOMOTO CO. INC (JP) | 2009-01-01 | — | — | US | disclosed |
| EP-2009003-A1 | Production method of diaminopyrimidine compounds | Ajinomoto Co., Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |
| US-20050165234-A1 | Process for preparing pyrimidine compound | AJINOMOTO CO. INC (JP) | 2005-07-28 | — | — | US | disclosed |
| EP-1553090-A1 | PROCESS FOR PRODUCING PYRIMIDINE COMPOUND | Ajinomoto Co., Inc. (JP) | 2005-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005560-A1 | PRODUCTION METHOD OF DIAMINOPYRIMIDINE COMPOUNDS | DPYD, DHPS, UMPS | RECQL 1128/4885MEN1 2530/4885KMT2A 1803/4885 |
| US-20050165234-A1 | Process for preparing pyrimidine compound | SERPINB1, CMA1, CTRC | RECQL 357/4885MEN1 906/4885KMT2A 2756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.